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. 2022 Nov 25;13:1057571. doi: 10.3389/fphar.2022.1057571

TABLE 2.

The effects of propofol on postoperative prognosis of tumors.

Study type Cancer type Research design Outcomes Ref
Retrospective Gastric cancer Propofol vs. Sevoflurane Improved survival Zheng et al. (2018)
Retrospective Gastric cancer Propofol vs. Desflurane Improved survival and reduced the risk of recurrence Huang et al. (2020b)
Retrospective Hepatocellular carcinoma Propofol vs. Inhalation anesthetics Decreased 2-year recurrence Koo et al. (2020)
Retrospective Hepatocellular carcinoma Propofol vs. Desflurane Better survival Lai et al. (2019a)
Retrospective Hepatocellular carcinoma Propofol vs. Sevoflurane Reduced mortality and recurrence Meng et al. (2020)
Retrospective Intrahepatic cholangiocarcinoma Propofol vs. Desflurane Improved survival and reduced the recurrence Lai et al. (2019b)
Retrospective Colon cancer Propofol vs. Desflurane Better survival Wu et al. (2018)
Retrospective Esophageal cancer Propofol vs. Inhalation anesthetics Better overall and recurrence-free survival Jun et al. (2017)
Retrospective Pancreatic cancer Propofol vs. Desflurane Improved survival Lai et al. (2020a)
Prospective Bladder cancer Propofol vs. Sevoflurane Improved disease-free Survival Guerrero Orriach et al. (2020)
Retrospective Prostate cancer Propofol vs. Desflurane Improved overall survival Lai et al. (2020b)
Retrospective Lung cancer Propofol vs. Inhalation anesthetics Better prognosis Hayasaka et al. (2021)
Retrospective Glioblastoma Propofol vs. Desflurane Better survival Huang et al. (2021)
Retrospective Breast cancer Propofol vs. Sevoflurane Better survival Enlund et al. (2020)
Retrospective Breast cancer Propofol vs. Sevoflurane Reduced local regional recurrence (Zhang et al., 2021b), (Zhang et al., 2022b)
Retrospective Breast cancer Propofol vs. Desflurane No difference Huang et al. (2019)
Retrospective Breast cancer Propofol vs. Inhalation anesthetics No difference Yoo et al. (2019)
Retrospective Breast cancer Propofol vs. Sevoflurane No difference Shiono et al. (2020)
Prospective Breast cancer Propofol vs. Sevoflurane No difference Yan et al. (2018)
Retrospective Gastric cancer Propofol vs. Inhalation anesthetics No difference Oh et al. (2019)
Retrospective Digestive tract tumor Propofol vs. Inhalation anesthetics No difference Makito et al. (2020)
Retrospective Glioblastoma Propofol vs. Sevoflurane No difference Schmoch et al. (2021)
Retrospective Glioma Propofol vs. Sevoflurane No difference Dong et al. (2020)