Table 1.
Characteristics of the Study Population by inclusion in the Analytic Sample and Enrollment in EARLI
| Analytic sample (n = 173) | EARLI n = (273) | |
|---|---|---|
|
| ||
| Child Sex, n(%) | ||
| Male | 89 (51.5%) | 131 (48.0%) |
| Female | 84 (48.6%) | 116 (42.5%) |
| Unknown | -- | 26 (9.5%) |
|
| ||
| Pre-pregnancy BMI, median(IQR) | 25.8 (23.3, 30.9) | 25.7 (23.0, 31.0) |
|
| ||
| Maternal age, median(IQR) | 34 (31, 37) | 34 (31, 37) |
|
| ||
| Maternal education level, n(%) | ||
| High school or less | 21 (12.1%) | 32 (11.7%) |
| Some college | 51 (29.5%) | 72 (26.4%) |
| College degree | 52 (30.1%) | 72 (26.4%) |
| Graduate school or above | 48 (27.8%) | 70 (25.6%) |
| Unknown | 1 (0.6%) | 27 (9.9%) |
|
| ||
| Maternal race/ethnicity, n(%) | ||
| Non-Hispanic White | 94 (54.3%) | 137 (50.2%) |
| Hispanic | 31 (17.9%) | 42 (15.4%) |
| Other race | 48 (27.8%) | 75 (27.5%) |
| Unknown race | -- | 19 (7.0%) |
|
| ||
| Income, n(%) | ||
| Less than $50,000 | 43 (24.9%) | 66 (24.2%) |
| $50,000 to $99,999 | 62 (35.8%) | 88 (32.2%) |
| $100,000+ | 68 (39.3%) | 100 (36.6%) |
| Unknown | -- | 19 (7.0%) |
|
| ||
| Pregnancy complicationsa, n(%) | ||
| None | 147 (85.0%) | 232 (85.0%) |
| At least 1 | 26 (15.0%) | 41 (15.0%) |
|
| ||
| Smoking during pregnancy, n(%) | ||
| Smoker or household exposure | 10 (5.8%) | 10 (3.7%) |
| Non-smoker, no household exposure | 131 (75.7%) | 176 (64.5%) |
| Unknown | 32 (18.5%) | 87 (31.9%) |
|
| ||
| Prenatal vitamin during 1st month | ||
| Yes | 99 (57.2%) | 126 (46.2%) |
| No | 73 (42.2%) | 84 (30.8%) |
| Unknown | 1 (0.6%) | 63 (23.1%) |
|
| ||
| Folic acid supplementation during 1st month | ||
| Yes | 10 (5.8%) | 19 (7.0%) |
| No | 162 (93.6%) | 191 (70.0%) |
| Unknown | 1 (0.6%) | 63 (23.1%) |
|
| ||
| Alcohol consumptionc, median (IQR) | 0.01 (0.01 – 0.03) | 0.01 (0.01–0.03) |
|
| ||
| Total SRS raw score, mean (SD)c | 36.3 (29.0) | 37.7 (28.4) |
|
| ||
| MSEL-ELC score, mean (SD)d | 99.0 (20.6) | 98.1 (21.1) |
|
| ||
| ASD diagnosis, n (%) | ||
| Typically developing | 80 (46.2%) | 91 (33.3%) |
| Non-typically developing | 52 (30.1%) | 61 (22.3%) |
| ASD | 32 (18.5%) | 43 (15.8%) |
| Unknown | 9 (5.2%) | 78 (28.6%) |
a
Included women who reported pre-eclampsia, gestational diabetes or medication use for high blood pressure (indicative of hypertension) in either this or the prior pregnancy.
b
Average number of drinks per day in pregnancy weeks 1–20
c
24 participants in the analytic sample and 77 participants from the full sample (EARLI) did not have SRS scores
d
10 participants in the analytic sample and 62 participants from the full sample (EARLI) did not have MSEL-ELC scores