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. 2022 Aug 3;27(12):e949–e956. doi: 10.1093/oncolo/oyac147

Table 4.

Treatment efficacy outcomes.

Characteristic Abiraterone
cohort (n = 86) n (%) or [IQR, 95% CI]
Enzalutamide
cohort (n = 148) n (%) or [IQR, 95% CI]
All patients
(n = 234) n (%) or [IQR, 95% CI]
PSA50 58 (69) 106 (73) 164 (72)
NA 2 (2) 3 (2) 5 (2)
PSA Δ median (−83) [−97/-30] (−85) [−98/-42] (−85) [−98/−39]
Median FU, mo. 17.5 [11.9-23.1] 14.6 [12.1-17.1] 15.4 [12.1-18.7]
PFS, median, mo. 28.4 [24.2-32.5] 23.1 [18.2-28.1) 26.0 [22.8-29.3]
OS, median, mo. 48.8 [34.3-63.3] 42.3 [39.1-45.4] 48.8 [36.8-60.8]

Abbreviations: CI, confidence intervals; Δ, difference between the PSA baseline and best response values; FU, follow-up; mo., months; NA, not assessable; OS, overall survival; PSA50, decline in the PSA ≥50%; rPFS, radiographic progression-free survival.