Table 4.
Characteristic | Abiraterone cohort (n = 86) n (%) or [IQR, 95% CI] |
Enzalutamide cohort (n = 148) n (%) or [IQR, 95% CI] |
All patients (n = 234) n (%) or [IQR, 95% CI] |
---|---|---|---|
PSA50 | 58 (69) | 106 (73) | 164 (72) |
NA | 2 (2) | 3 (2) | 5 (2) |
PSA Δ median | (−83) [−97/-30] | (−85) [−98/-42] | (−85) [−98/−39] |
Median FU, mo. | 17.5 [11.9-23.1] | 14.6 [12.1-17.1] | 15.4 [12.1-18.7] |
PFS, median, mo. | 28.4 [24.2-32.5] | 23.1 [18.2-28.1) | 26.0 [22.8-29.3] |
OS, median, mo. | 48.8 [34.3-63.3] | 42.3 [39.1-45.4] | 48.8 [36.8-60.8] |
Abbreviations: CI, confidence intervals; Δ, difference between the PSA baseline and best response values; FU, follow-up; mo., months; NA, not assessable; OS, overall survival; PSA50, decline in the PSA ≥50%; rPFS, radiographic progression-free survival.