Table 2.
Number of patients receiving antihypertensive therapy during follow-up stratified for the occurrence of PE.
| Antihypertensive therapy | No PE n = 243,834 | With PE n = 14,510 | r value | |||
|---|---|---|---|---|---|---|
| Betablocker | 1y | 3562 | (1.5) | 1210 | (8.3) | 0.118 |
| 2y | 4858 | (2.0) | 1368 | (9.4) | 0.112 | |
| 3y | 5888 | (2.4) | 1485 | (10.2) | 0.108 | |
| 5y | 7102 | (2.9) | 1626 | (11.2) | 0.106 | |
| 7.5y | 7572 | (3.1) | 1679 | (11.6) | 0.105 | |
| ACE inhibitor | 1y | 1278 | (0.5) | 606 | (4.2) | 0.099 |
| 2y | 1927 | (0.8) | 799 | (5.5) | 0.106 | |
| 3y | 2487 | (1.0) | 891 | (6.1) | 0.104 | |
| 5y | 3246 | (1.3) | 1027 | (7.1) | 0.104 | |
| 7.5y | 3639 | (1.5) | 1100 | (7.6) | 0.104 | |
| Angiotensin II receptor blocker | 1y | 370 | (0.2) | 179 | (1.2) | 0.054 |
| 2y | 574 | (0.2) | 239 | (1.6) | 0.058 | |
| 3y | 756 | (0.3) | 283 | (2.0) | 0.06 | |
| 5y | 1014 | (0.4) | 336 | (2.3) | 0.061 | |
| 7.5y | 1151 | (0.5) | 374 | (2.6) | 0.063 | |
| Calcium channel blocker | 1y | 1364 | (0.6) | 526 | (3.6) | 0.083 |
| 2y | 1675 | (0.7) | 616 | (4.2) | 0.087 | |
| 3y | 1992 | (0.8) | 684 | (4.7) | 0.089 | |
| 5y | 2411 | (1.0) | 755 | (5.2) | 0.088 | |
| 7.5y | 2645 | (1.1) | 799 | (5.5) | 0.089 | |
| Diuretics | 1y | 1340 | (0.5) | 370 | (2.5) | 0.057 |
| 2y | 1727 | (0.7) | 447 | (3.1) | 0.06 | |
| 3y | 2111 | (0.9) | 515 | (3.5) | 0.062 | |
| 5y | 2590 | (1.1) | 606 | (4.2) | 0.065 | |
| 7.5y | 2825 | (1.2) | 646 | (4.5) | 0.066 | |
| ACE inhibitor combinations | 1y | 299 | (0.12) | 183 | (1.26) | 0.061 |
| 2y | 445 | (0.18) | 229 | (1.58) | 0.063 | |
| 3y | 566 | (0.23) | 264 | (1.82) | 0.064 | |
| 5y | 777 | (0.32) | 310 | (2.14) | 0.065 | |
| 7.5y | 890 | (0.37) | 332 | (2.29) | 0.064 | |
| Angiotensin II receptor blocker combinations | 1y | 172 | (0.07) | 102 | (0.70) | 0.044 |
| 2y | 281 | (0.12) | 140 | (0.96) | 0.048 | |
| 3y | 366 | (0.15) | 164 | (1.13) | 0.05 | |
| 5y | 480 | (0.20) | 196 | (1.35) | 0.052 | |
| 7.5y | 548 | (0.22) | 207 | (1.43) | 0.051 | |
Data are presented as absolute numbers (cumulative percentages) and were compared using χ2 test with Yates’ continuity correction. Bold values indicate r values > 0.1. P values not shown, as for each row p < 0.0001. PE: preeclampsia; ACE: angiotensin-converting enzyme.