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. 2022 Dec 8;12:21282. doi: 10.1038/s41598-022-25823-w

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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CRC patient m⁷G-related genes expression and mutational profiles. (A) The expression of 29 m⁷G-associated genes in normal and CRC patient tumor tissue samples. (B) Correlation heat map of expression between m⁷g genes, plotted using the corrplot function in the corrplot package of the R language (version 4.1.2, https://www.r-project.org/). (C) The co-occurrence and mutual exclusivity of these 29 m⁷g-related genes after mutation were plotted using the somaticinteraction function in the maftools package of the R language (version 4.1.2). (D) Waterfall plots representing the mutational characteristics of these 29 m⁷g-related genes were drawn using the oncoplot function in the maftools package of the R language (version 4.1.2). *P < 0.05; **P < 0.01; ***P < 0.001.