Table 2. Cumulative incidence of thrombosis in children after 7, 15, 30, 45, and 60 days of PICC insertion.

Variables	Cumulative incidence of thrombosis (%)						Log-rank test
	7 days after catheterization	15 days after catheterization	30 days after catheterization	45 days after catheterization	60 days after catheterization		χ2	P
Overall	15.27	30.81	36.68	46.27	54.67		–	–
Age (months)							8.254	0.004
<12	15.88	38.68	46.34	56.27	56.27
≥12	14.66	20.87	24.58	32.96	56.01
Limb movement training							7.142	0.008
Yes	12.58	22.23	29.34	38.17	38.17
No	17.18	36.36	41.32	51.25	67.50
20% mannitol or glycerol fructose							20.026	<0.001
Yes	27.02	48.40	50.46	70.28	85.14
No	13.16	27.61	34.48	38.57	43.30
Furosemide							6.212	0.013
Yes	16.28	34.69	42.57	54.44	64.50
No	13.84	24.34	25.60	25.60	25.60
Catheter placing personnel							50.018	<0.001
PICU personnel	26.28	49.52	57.20	75.54	75.54
Operating room anesthetist	10.38	21.51	26.15	26.15	41.97
Insertion length (cm)							21.85	<0.001
≥9	23.85	45.30	53.33	62.66	81.33
<9	12.32	25.89	30.54	39.66	39.66
Fibrinogen							4.328	0.037
≤1.7 g/L	16.12	37.29	42.59	53.61	59.41
>1.7 g/L	14.82	26.77	33.01	40.46	50.38
Activated partial prothrombin time							9.433	0.002
>32 s	17.48	38.61	45.18	53.62	58.77
≤32 s	13.48	22.66	27.51	37.87	50.30
D-dimer							15.543	<0.001
>1.5 mg/L	20.11	39.88	46.91	55.89	55.89
≤1.5 mg/L	11.35	21.78	25.76	35.04	58.24

PICC, peripherally inserted central catheter; PICU, pediatric intensive care unit.