Table 3.
Multivariable Regressions between Plasma Biomarkers and Neuropathology: regression coefficient (standard error) and p-value for each term.
| Amyloid-β | Tau | Cerebrovascular disease | |||
|---|---|---|---|---|---|
| Thal Phase | Neuritic Plaques |
Braak Score | Strozyk score |
Kalaria score |
|
| Aβ42/40 | −1.4 (21) p = 0.9 | −30 (22) p = 0.62 | −14 (16) p = 0.54 | 43 (17) p = 0.04 | 101 (29) p = 0.001 |
| Partial R 2 | 0 | 0.034 | 0.014 | 0.102 | 0.175 |
| T-tau | 0.05 (0.07) p = 0.82 | 0.07 (0.05) p = 0.84 | 0.04 (0.053) p = 1.0 | 0.10 (0.06) p = 0.90 | 0.05 (0.11) p = 0.96 |
| Partial R 2 | 0.009 | 0.039 | 0.011 | 0.048 | 0.004 |
| NfL | 0.002 (0.006) p = 0.88 | 0.001 (0.006) p = 0.96 | 0.005 (0.004) p = 0.74 | 0.014 (0.005) p = 0.011 | 0.025 (0.008) p = 0.002 |
| Partial R 2 | 0.003 | 0.003 | 0.019 | 0.14 | 0.14 |