Table 3.
Transfusions and other outcomes
| Control | Number of units of blood removed | P | |||||||
|---|---|---|---|---|---|---|---|---|---|
|
|
|
||||||||
| 0 units n=596 | 1 unit n=482 | 2 units n=1257 | 3 units n=474 | ||||||
|
|
|
|
|
||||||
| n | % | n | % | n | % | n | % | ||
| Intraoperative transfusion | |||||||||
| Red cells | 449 | 75 | 229A | 48 | 504A, B | 40 | 140A, B, C | 30 | <.001 |
| Plasma | 313 | 53 | 132A | 27 | 371A | 30 | 89A, B, C | 19 | <.001 |
| Platelet | 341 | 57 | 143A | 30 | 426A | 34 | 108A, b, C | 23 | <.001 |
| Cryoprecipitate | 82 | 14 | 27 | 6 | 155 | 12 | 37 | 8 | 0.122 |
| Postoperative transfusions | |||||||||
| Red cells | 139 | 23 | 68a | 14 | 110a, b | 9 | 33a, b | 7 | <0.001 |
| Plasma | 30 | 5 | 8a | 2 | 26a | 2 | 5a | 1 | <0.001 |
| Platelets | 39 | 7 | 14a | 3 | 33a | 3 | 9a | 2 | <0.001 |
| Cryoprecipitate | 2 | 0.3 | 0 | 0 | 2 | 0.2 | 0 | 0 | 0.399 |
| Any transfusions | |||||||||
| Red cells | 471 | 79 | 258a | 54 | 542a, b | 43 | 154a, b, c | 32 | <0.001 |
| Plasma | 316 | 53 | 133a | 28 | 375a | 30 | 90a, b, c | 19 | <0.001 |
| Platelets | 346 | 58 | 145a | 30 | 434a | 35 | 114a, B, c | 24 | <0.001 |
| Cryoprecipitate | 346 | 14 | 27a | 6 | 156b | 12 | 37a, c | 8 | <0.001 |
|
| |||||||||
| Median | IQR | Median | IQR | Median | IQR | Median | IQR | P | |
|
| |||||||||
| Intraoperative transfusions | |||||||||
| Red cells (units) | 3 | (1, 6) | 0A | (0, 2) | 0A | (0, 2) | 0A, B, C | (0, 1) | <0.001 |
| Plasma (units) | 1 | (0, 4) | 0A | (0, 1) | 0A, b | (0, 2) | 0A, C | (0, 0) | <0.001 |
| Platelets (units) | 1 | (0, 4) | 0A | (0, 1) | 0A, b | (0, 2) | 0A, C | (0, 0) | <0.001 |
| Cryoprecipitate (units) | 0 | (0, 0) | 0A | (0, 0) | 0B | (0, 0) | 0A, C | (0, 0) | 0.009 |
| Postoperative transfusions | |||||||||
| Red cells (units) | 0 | (0, 0) | 0a | (0, 0) | 0a, b | (0, 0) | 0a, b, c | (0, 0) | <0.001 |
| Plasma (units) | 0 | (0, 0) | 0a | (0, 0) | 0a, b | (0, 0) | 0a, b, c | (0, 0) | <0.001 |
| Platelets (units) | 0 | (0, 0) | 0a | (0, 0) | 0a, b | (0, 0) | 0a, b, c | (0, 0) | <0.001 |
| Cryoprecipitate (units) | 0 | (0, 0) | 0a | (0, 0) | 0a, b | (0, 0) | 0a, b, c | (0, 0) | 0.400 |
| Any transfusions | |||||||||
| Red cells (units) | 3 | (1, 6) | 0a | (0, 2) | 0a, b | (0, 2) | 0a, b, c | (0, 1) | <0.001 |
| Plasma (units) | 1 | (0, 4) | 0a | (0, 1) | 0a, b | (0, 2) | 0A, b, c | (0, 0) | <0.001 |
| Platelets (units) | 1 | (0, 4) | 0a | (0, 1) | 0a, b | (0, 2) | 0b, c | (0, 0) | <0.001 |
| Cryoprecipitate (units) | 0 | (0, 0) | 0a | (0, 0) | 0a, b | (0, 0) | 0a, b, c | (0, 0) | <0.001 |
| Other Outcomes | |||||||||
|
| |||||||||
| Mean | SD | Mean | SD | Mean | SD | Mean | SD | P | |
|
| |||||||||
| Minimum arterial pH | 7.32 | 0.09 | 7.34A | 0.06 | 7.33a, b | 0.06 | 7.32B, C | 0.05 | 0.744 |
| Maximum lactic acid (mmol/L) | 3.6 | 2.6 | 2.6A | 1.4 | 3.0A, B | 1.8 | 3.6B, C | 1.7 | 0.410 |
| Minimum bicarbonate (mEq/L) | 22.0 | 2.8 | 22.3 | 2.3 | 22.4A | 2.3 | 22.1c | 2.1 | 0.128 |
| First ICU hematocrit (%) | 27.5 | 4.4 | 27.0 | 4.3 | 28.1a, B | 4.0 | 28.3A, B | 4.0 | <0.001 |
| First ICU platelet count (1000/m) | 156 | 58 | 145A | 52 | 144A | 50 | 127A, B, C | 39 | <0.001 |
| Reexploration | 23 | 4 | 14 | 3 | 32 | 3 | 12 | 3 | 0.432 |
| KDIGO stage 1 | 165 | 28 | 141 | 29 | 301a | 24 | 107a | 23 | 0.097 |
| KDIGO stage 2 | 23 | 4 | 15 | 3 | 43 | 3 | 18 | 4 | 0.917 |
| KDIGO stage 3 | 39 | 7 | 16 | 3 | 25A | 2 | 8A, B | 2 | <.001 |
A<0.01, a<0.05 compared to Control Group, B<0.01, b<0.05 compared to autologous blood removal without fluid replacement group with 1 unit removed, C<.01, c<.05 compared to autologous blood removal without fluid replacement group with 2 units removed. Any transfusion is intraoperative+postoperative transfusion. KDIGO – Kidney Disease: Improving Global Outcomes. SD – standard deviation. IQR – interquartile range