Table 5.
Adjusted odds ratio in patients with 1, 2, or 3 units of autologous blood removed compared to patients who had no autologous blood removed (Control group). Regressions used the adjusted intravenous fluids and cardiopulmonary bypass volume adjusted for the volume of albumin given (3:1 for 5% and 15:1 for 25% albumin). Any transfusion is sum of intraoperative and postoperative
| Number of units of blood removed | Autologous blood removal without fluid replacement | ||||||||
|---|---|---|---|---|---|---|---|---|---|
|
| |||||||||
| 1 unit | 2 units | 3 units | |||||||
|
|
|
|
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| Odds ratio 95% CI | P | Odds ratio 95% CI | P | Odds ratio 95% CI | P | ||||
| Factor | |||||||||
| Calcium administration | 2.34 | (0.60, 9.16) | 0.224 | 2.73 | (0.94, 7.96) | 0.066 | undef | (0,) | 0.990 |
| Any vasopressor infusion | 1.70 | (0.87, 3.30) | 0.118 | 2.23 | (1.32, 3.77) | 0.003 | 3.52 | (1.61, 7.69) | 0.002 |
| Ephedrine administration | 1.08 | (0.76, 1.55) | 0.663 | 1.54 | (1.14, 2.07) | 0.004 | 1.51 | (1.02, 2.24) | 0.039 |
| Intraoperative transfusion | |||||||||
| Red cell | 0.36 | (0.25, 0.52) | <0.001 | 0.25 | (0.18, 0.34) | <0.001 | 0.09 | (0.06, 0.14) | <0.001 |
| Plasma | 0.49 | (0.35, 0.68) | <0.001 | 0.36 | (0.27, 0.48) | <0.001 | 0.08 | (0.05, 0.12) | <0.001 |
| Platelet | 0.46 | (0.33, 0.63) | 0.001 | 0.39 | (0.30, 0.52) | <0.001 | 0.10 | (0.07, 0.16) | <0.001 |
| Cryoprecipitate | 0.52 | (0.29, 0.91) | 0.023 | 0.73 | (0.49, 1.08) | 0.118 | 0.16 | (0.09, 0.29) | <0.001 |
| Any transfusions | |||||||||
| Red cells (units) | 0.41 | (0.28, 0.60) | <0.001 | 0.24 | (0.17, 0.33) | <0.001 | 0.09 | (0.05, 0.14) | <0.001 |
| Plasma (units) | 0.48 | (0.34, 0.68) | <0.001 | 0.35 | (0.26, 0.48) | <0.001 | 0.08 | (0.05, 0.12) | <0.001 |
| Platelets (units) | 0.43 | (0.31, 0.61) | <0.001 | 0.38 | (0.28, 0.51) | <0.001 | 0.11 | (0.07, 0.16) | <0.001 |
| Cryoprecipitate (units) | 0.52 | (0.28, 0.95) | 0.033 | 0.83 | (0.55, 1.27) | 0.388 | 0.19 | (0.10, 0.37) | <0.001 |
| KDIGO stage 1 or worse | 1.14 | (0.84, 1.55) | 0.398 | 0.99 | (0.76, 1.29) | 0.970 | 0.96 | (0.66, 1.37) | 0.810 |
| KDIGO stage 2 or worse | 0.64 | (0.34, 1.25) | 0.197 | 0.85 | (0.51, 1.41) | 0.528 | 0.72 | (0.35, 1.51) | 0.386 |
KDIGO – Kidney disease improving global outcome, within the first three postoperative days. Undef – undefined