Table 2.
Outcomes of the study population according to targeted temperature
| All patients | Original cohort, N, % | Crude analysis OR (95% CI) |
Multivariable analysis AOR (95% CI)a |
After adjustment of IPW, % | OR (95% CI)b | |||
|---|---|---|---|---|---|---|---|---|
| n-TTM | h-TTM | n-TTM | h-TTM | |||||
| N = 890 | N = 249 | N = 641 | ||||||
| 30-Day neurological favourable outcome | 143 (16.1) | 41 (16.5) | 102 (15.9) | 0.96 (0.65–1.43) | 0.91 (0.58–1.43) | 15.3 | 15.4 | 1.01 (0.67–1.54) |
| 30-Day survival | 318 (35.7) | 88 (35.3) | 230 (35.9) | 1.02 (0.75–1.39) | 1.00 (0.71–1.41) | 34.3 | 35.5 | 1.05 (0.76–1.46) |
| Completion of TTM | 566 (63.6) | 163 (65.5) | 403 (62.9) | 0.89 (0.66–1.21) | 0.81 (0.57–1.16) | 67.0 | 62.2 | 0.81 (0.58–1.13) |
Values are expressed numbers (percentages) unless indicated otherwise
TTM targeted temperature management, n-TTM normothermic TTM, h-TTM hypothermic TTM, OR odds ratio, AOR adjusted odds ratio, CI confidence interval, IPW inverse probability weighting
aShown is the AOR from the multivariable logistic regression analysis adjusted for age, sex, cause of arrest, bystander witness, bystander CPR, use of public-access AEDs, prehospital epinephrine administration, prehospital advanced airway management, time from EMS call to contact with the patients, time from EMS contact with the patients to hospital arrival, type of centre, the annual volume of ECMO used for OHCA at each centre, success of PCI, timing of ECMO start, time from hospital arrival to induction of ECMO, and TTM induction time
bShown is the odds ratio from the univariable logistic regression analysis with IPW