Table 2.
Changes of ocular variables during regression in FS-LASIK and TPRK groups before treatment, after treatment and after drug withdrawal (Mean ± SD)
| FS-LASIK (n = 45 eyes) | TPRK (n = 44 eyes) | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Initial | End | finish | Pa | Pb | Initial | End | finish | Pa | Pb | |
| UDVA (logMAR) | 0.15 ± 0.07 | 0.03 ± 0.06 | 0.03 ± 0.07 | < 0.001 | 0.823 | 0.11 ± 0.04 | -0.02 ± 0.04 | -0.02 ± 0.04 | < 0.001 | 0.710 |
| CDVA (logMAR) | -0.02 ± 0.03 | -0.02 ± 0.04 | -0.02 ± 0.03 | 0.420 | 0.323 | -0.03 ± 0.04 | -0.03 ± 0.04 | -0.03 ± 0.04 | 0.083 | 0.083 |
| Sphere(D) | -0.81 ± 0.42 | -0.11 ± 0.36 | -0.14 ± 0.39 | < 0.001 | 0.291 | -0.53 ± 0.13 | -0.02 ± 0.19 | -0.05 ± 0.20 | < 0.001 | 0.400 |
| Cylinder(D) | -0.21 ± 0.17 | -0.11 ± 0.16 | -0.13 ± 0.26 | 0.001 | 0.679 | -0.23 ± 0.18 | -0.08 ± 0.13 | -0.10 ± 0.13 | < 0.001 | 0.372 |
| SE(D) | -0.92 ± 0.42 | -0.16 ± 0.37 | -0.21 ± 0.46 | < 0.001 | 0.251 | -0.64 ± 0.14 | -0.06 ± 0.19 | -0.09 ± 0.21 | < 0.001 | 0.220 |
| IOP (mmHg) | 12.00 ± 2.08 | 11.82 ± 2.02 | 11.89 ± 1.71 | 0.290 | 0.691 | 11.95 ± 1.41 | 11.95 ± 1.63 | 12.07 ± 1.44 | 1.000 | 0.342 |
| Axial length (mm) | 26.46 ± 1.02 | 26.46 ± 1.04 | 26.46 ± 1.04 | 0.069 | 0.719 | 26.42 ± 0.96 | 26.42 ± 0.95 | 26.42 ± 0.95 | 0.473 | 0.611 |
| CCT (µm) | 444.80 ± 28.40 | 437.31 ± 28.52 | 438.38 ± 27.62 | < 0.001 | 0.130 | 414.98 ± 33.05 | 408.11 ± 34.81 | 408.93 ± 32.85 | < 0.001 | 0.274 |
| cET(µm) | 65.02 ± 4.12 | 59.42 ± 3.70 | 60.02 ± 4.82 | < 0.001 | 0.078 | 63.89 ± 3.71 | 58.05 ± 3.98 | 58.59 ± 3.20 | < 0.001 | 0.095 |
| mET (µm) | 61.63 ± 2.91 | 57.24 ± 3.10 | 57.55 ± 3.97 | < 0.001 | 0.253 | 62.52 ± 2.82 | 57.33 ± 2.53 | 57.67 ± 2.27 | < 0.001 | 0.067 |
| pET (µm) | 52.06 ± 2.97 | 50.86 ± 1.85 | 51.26 ± 2.14 | 0.007 | 0.082 | 54.54 ± 2.23 | 51.93 ± 1.24 | 52.07 ± 1.11 | < 0.001 | 0.286 |
| KI front (D) | 37.90 ± 1.10 | 37.10 ± 1.23 | 37.14 ± 1.18 | < 0.001 | 0.200 | 37.37 ± 1.41 | 36.61 ± 1.52 | 36.64 ± 1.43 | < 0.001 | 0.235 |
| K2 front (D) | 38.97 ± 1.15 | 38.07 ± 1.26 | 38.11 ± 1.27 | < 0.001 | 0.140 | 38.36 ± 1.55 | 37.63 ± 1.68 | 37.65 ± 1.40 | < 0.001 | 0.790 |
| K1 Back (D) | -6.19 ± 0.21 | -6.18 ± 0.20 | -6.17 ± 0.20 | 0.561 | 0.110 | -6.18 ± 0.21 | -6.18 ± 0.21 | -6.18 ± 0.22 | 0.352 | 0.323 |
| K2 Back (D) | -6.57 ± 0.26 | -6.59 ± 0.25 | -6.58 ± 0.27 | 0.192 | 0.200 | -6.58 ± 0.25 | -6.57 ± 0.25 | -6.57 ± 0.25 | 0.643 | 0.710 |
SD standard deviation; UDVA uncorrected distant visual acuity; CDVA corrected distance visual acuity; SE spherical equivalent; logMAR logarithm of the minimum angle of resolution; D diopters; IOP intraocular pressure; CCT central cornea thickness; OZ optical zone; AD ablation depth; cET central corneal epithelial thickness; mET paracentral epithelial thickness; pET midperipheral epithelial thickness; K front anterior corneal curvature; K Back posterior corneal curvature; Initial before drug treatment; End three months after drug treatment; Finish three months after drug withdrawal; a compared with before drug treatment; b compared with three months after drug treatment