Table 3.
eBL association with unique recombination events
| Event | CDS cut by start breakpoint | CDS cut by end breakpoint | Frequency in eBLs (%) | Frequency in healthy (%) | Without controlling for viral type | Controlling for viral type | ||
|---|---|---|---|---|---|---|---|---|
| ORa (95% CI) | p value | ORb (95% CI) | p value | |||||
| 47 | BRLF1, BZLF1 | BDLF3.5, BDLF4 | 16/54 (29.6) | 3/32 (9.4) | 4.07 (1.21–1.87) | 0.038a | 3.31 (0.99–1.58) | 0.089b |
| 50 | LMP2A, LMP2B | EBNA2 | 17/54 (31.5) | 1/32 (3.1) | 14.24 (2.69–2.84) | 0.012a | 12.36 (2.18–2.34) | 0.020b |
CDS coding sequence, eBL endemic Burkitt lymphoma, OR odds ratio, Ref reference
Bold text indicates a statistical significance with a p value < 0.05. aUnivariate and bMultivariate logistic regression was used to compute the Odds Ratios and p values non-significant p value by univariate analysis