Table 2.
FRAX* by quartiles at age 75 and frailty score, fracture and falls
| All variables at 75y | Low FRAX Q1 (<=19) |
FRAX Q2 (20–26) |
FRAX Q3 (27–33) |
High FRAX Q4 (34+) |
No | p-value# Overall |
p-value Q1 vs Q4 |
||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| n = 303 | n = 214 | n = 279 | n = 227 | ||||||||
| Mean | range | Mean | range | Mean | range | Mean | range | ||||
| FRAX MOF no BMD | 16.9 | (12–19) | 22.6 | (20 - 26) | 30.0 | (27–33) | 41.8 | (34–69) | – | – | |
| Frailty index | 0.15 | (0.00–0.65) | 0.16 | (0.00–0.70) | 0.16 | (0.00–0.72) | 0.19 | (0.00–0.77) | 1023 | 0.015 | 0.004 |
| Fractures | No | (%) | No | (%) | No | (%) | No | (%) | |||
| Prior any fx (20-75y) | 30 | (6.7) | 48 | (10.7) | 187 | (41.7) | 183 | (40.8) | 448 | < 0.001 | < 0.001 |
| Prior any fx (50-75y) | 21 | (5.6) | 40 | (10.7) | 156 | (41.7) | 157 | (42.0) | 374 | < 0.001 | < 0.001 |
| Prior MOF (50-75y) | 19 | (8.1) | 23 | (9.8) | 101 | (43.0) | 92 | (39.1) | 235 | < 0.001 | < 0.001 |
| Falls in the last year | No | (%) | No | (%) | No | (%) | No | (%) | |||
| 1 or more falls reported | 66 | (26.1) | 45 | (17.5) | 75 | (29.6) | 67 | (26.5) | 253 | 0.118 | 0.057 |
| 3 or more falls reported | 18 | (27.7) | 10 | (15.4) | 21 | (32.3) | 16 | (24.6) | 65 | 0.609 | 0.661 |
| Bone mineral density | Median | IQR | Median | IQR | Median | IQR | Median | IQR | |||
| Femoral neck T-score | −1.50 | (1.65) | −1.80 | (1.60) | −1.98 | (1.48) | −2.34 | (1.37) | 946 | < 0.001 | < 0.001 |
| Femoral neck BMD (g/cm2) | 0.800 | (0.200) | 0.764 | (0.192) | 0.742 | (0.178) | 0.700 | (0.164) | 946 | < 0.001 | < 0.001 |
*FRAXMOF no BMD. Reported values are means, unless otherwise stated. # p-values calculated by ANOVA, Kruskal Wallace or Chi-square as appropriate