Table 2.
Univariate analysis of DFS and OS in esophageal squamous cell carcinoma
| Variable | DFS | OS | ||||
|---|---|---|---|---|---|---|
| Median | 95%CI | P | Median | 95%CI | P | |
| Sex | 0.037 | 0.027 | ||||
| Man | 28.6 | 21.8–35.5 | 35.2 | 27.2–43.3 | ||
| Woman | 42.9 | 22.3–63.4 | 55.7 | 21.9–89.6 | ||
| Age | 0.426 | 0.329 | ||||
| <65 years | 33.4 | 25.1–41.7 | 42.3 | 30.5–54.0 | ||
| ≥ 65 years | 26.4 | 20.5–32.4 | 30.0 | 20.4–39.4 | ||
| Tumor location | 0.699 | 0.670 | ||||
| Upper | 27.2 | 21.0–33.3 | 35.2 | 19.3–51.2 | ||
| Middle | 35.3 | 26.7–43.9 | 42.5 | 30.1–5.9 | ||
| Lower | 27.2 | 19.5–35.0 | 31.4 | 10.5–52.2 | ||
| Tumor length | 0.002 | 0.013 | ||||
| ≤ 4.0 cm | 42.9 | 32.4–53.3 | 49.1 | 36.9–61.4 | ||
| >4.0 cm | 26.4 | 20.7–32.2 | 29.9 | 19.4–40.4 | ||
| Differentiation | 0.799 | 0.664 | ||||
| G1 | 30.0 | 19.8–40.2 | 35.0 | 23.1–47.0 | ||
| G2 | 32.0 | 21.2–42.9 | 41.9 | 25.8–57.9 | ||
| G3 | 35.3 | 20.0–50.5 | 45.6 | 25.8–65.4 | ||
| p T stage | 0.001 | |||||
| T1 | 85.9 | 46.2–125.7 | 85.9 | NA | 0.002 | |
| T2 | 41.4 | 33.0–49.8 | 43.9 | 11.1–76.6 | ||
| T3 | 26.8 | 20.9–32.8 | 32.6 | 25.2–40.0 | ||
| T4 | 14.3 | 0.0–80.3 | 20.0 | 0.0–79.9 | ||
| p N stage | <0.001 | <0.001 | ||||
| N0 | 59.5 | 34.4–84.6 | 82.6 | 58.6–106.6 | ||
| N1 | 25.9 | 18.2–33.7 | 36.7 | 24.9–48.5 | ||
| N2 | 13.5 | 10.3–16.7 | 17.9 | 12.8–23.0 | ||
| N3 | 8.8 | 2.0–15.5 | 11.8 | 9.8–13.7 | ||
| p TNM stage | <0.001 | <0.001 | ||||
| I stage | 71.4 | 43.5–99.3 | 85.9 | NA | ||
| II stage | 55.7 | 26.3–85.1 | 66.6 | 57.4–97.8 | ||
| III stage | 18.8 | 11.7–25.9 | 45.7 | 21.5–31.3 | ||
| IV stage | 10.8 | 4.9–16.6 | 11.9 | 9.9–14.0 | ||
| Perineural invasion | <0.001 | <0.001 | ||||
| Present | 19.9 | 13.1–26.7 | 26.4 | 22.1–30.7 | ||
| Absent | 43.9 | 26.4–61.3 | 62.5 | 39.0–85.9 | ||