Table 4.
The correlation between PNI phenotypes and clinicopathological characteristics of esophageal squamous cell carcinoma
| Variable | Total | Subtypes of PNI | P value | |||
|---|---|---|---|---|---|---|
| 127 | PNI-a | PNI-b | PNI-c | PNI-d | ||
| Sex | 0.285 | |||||
| Man | 94 | 26(27.7%) | 29(30.9%) | 19(20.2%) | 20(21.2%) | |
| Woman | 33 | 9(27.3%) | 10(30.3%) | 11(33.3%) | 3(9.1%) | |
| Age | 0.515 | |||||
| <65 years | 105 | 27(25.7%) | 33(31.4%) | 27(25.7%) | 18(17.2%) | |
| ≥ 65 years | 22 | 8(36.4%) | 6(27.3%) | 3(13.6%) | 5(22.7%) | |
| Tumor location | 0.007 | |||||
| Upper | 7 | 1(14.3%) | 0(0) | 2(28.6%) | 4(57.1%) | |
| Middle | 88 | 29(33.0%) | 30(34.1%) | 20(22.7) | 9(10.2%) | |
| Lower | 32 | 5(15.6%) | 9(28.1%) | 8(25.0%) | 10(31.3%) | |
| Tumor length | 0.189 | |||||
| ≤ 4.0 cm | 61 | 14(23.0%) | 21(34.4%) | 18(29.5%) | 8(13.1%) | |
| >4.0 cm | 66 | 21(31.8%) | 18(27.3%) | 12(18.2%) | 15(22.7%) | |
| Differentiation | 0.584 | |||||
| G1 | 46 | 15(32.6%) | 12(26.1%) | 9(19.6%) | 10(21.7%) | |
| G2 | 51 | 12(23.5%) | 15(29.4%) | 16(31.4%) | 8(15.7%) | |
| G3 | 30 | 8(26.6%) | 12(40.0%) | 5(16.7%) | 5(16.7%) | |
| p T stage | 0.782 | |||||
| T1 | 7 | 1(14.3%) | 3(42.8%) | 1(14.3%) | 2(28.6%) | |
| T2 | 19 | 8(42.1%) | 5(26.3%) | 3(15.8%) | 3(15.8%) | |
| T3 | 97 | 24(24.7%) | 30(30.9%) | 25(25.8%) | 18(18.6%) | |
| T4 | 4 | 2(50.0%) | 1(25.0%) | 1(25.0%) | 0(0) | |
| p N stage | 0.144 | |||||
| N0 | 50 | 13(26.0%) | 20(40.0%) | 8(16.0%) | 9(18.0%) | |
| N1 | 40 | 14(35.0%) | 10(25.0%) | 9(22.5%) | 7(17.5%) | |
| N2 | 31 | 8(25.8%) | 9(29.0%) | 9(29.0%) | 5(16.2%) | |
| N3 | 6 | 0(0) | 0(0) | 4(66.7%) | 2(33.3%) | |
| p TNM stage | 0.151 | |||||
| I stage | 8 | 1(12.5%) | 5(62.5%) | 1(12.5%) | 1(12.5%) | |
| II stage | 42 | 11(25.6%) | 15(35.7%) | 7(16.7%) | 9(21.4%) | |
| III stage | 70 | 23(32.9%) | 18(25.7%) | 18(25.7%) | 11(15.7%) | |
| IV stage | 7 | 0(0) | 1(14.3%) | 4(57.1%) | 2(28.6%) | |