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. 2022 Dec 9;22:536. doi: 10.1186/s12872-022-02956-4

Table 2.

Adjusted CAC Volume and Density Among Those with DM or MetS

DM
(n = 668)
MetS
(n = 1122)
Neither DM/MetS
(n = 2028)
p value
CAC volume (95%CI) Overall 79.46 (71.97–87.72)§ 60.53 (55.46–66.08)‡ 51.77 (48.01–55.82) < 0.0001
Non-statin users 72.17 (64.44–80.81)§ 56.58 (51.72–61.89)* 48.61 (45.16–52.32) < 0.0001
Statin users 98.12 (80.60-119.44)§ 69.32 (56.62–84.88) 57.24 (47.59–68.85) < 0.0001
CAC density (95%CI) Overall 2.54 (2.49–2.59)§ 2.61 (2.57–2.65)‡ 2.69 (2.65–2.72) < 0.0001
Non-statin users 2.56 (2.51–2.62)§ 2.62 (2.57–2.66)† 2.68 (2.65–2.72) 0.0001
Statin users 2.53 (2.44–2.62)§ 2.65 (2.55–2.74)* 2.76 (2.67–2.84) < 0.0001

The mean CAC density (or ln(Volume)) was adjusted for ln(Volume) (or CAC density), age, sex, race/ethnicity, education, smoking status, statin use and hypertension medication

P values were calculated from ANOVA test among three groups (last column) and from student t-tests comparing DM vs. neither DM/MetS and MetS versus neither DM/MetS (presented as symbols)

CAC  Coronary artery calcium, DM  Diabetes mellitus, MetS  Metabolic syndrome

*p < 0.05, †p < 0.01, ‡ p< 0.001, §p < 0.0001.