Table 5.

Correlations between plasma and CSF NfL with the MRI findings in SLE patients

	Plasma NfL		CSF NfL
	n	r	p-value	n	r	p-value
White matter lesion volume a	65	0.14	0.26	29	0.21	0.29
Total white matter volume a	71	0.053	0.66	32	0.036	0.73
Total grey matter volume a	71	−0.092	0.45	32	−0.065	0.73
Subcortical grey matter volume a	71	−0.038	0.76	32	0.15	0.43
Cortex volume b	71	−0.004	0.97	32	−0.20	0.29
Corpus callosum volume a	71	−0.075	0.54	32	0.11	0.57
Thalamus volume a	71	−0.076	0.54	32	0.096	0.61
Hippocampus volume a	70	−0.057	0.65	32	0.10	0.59
Pallidum volume a	71	0.004	0.97	32	0.053	0.78
Putamen volume a	71	0.055	0.65	32	0.089	0.64
Caudate volume a	71	0.14	0.26	32	0.30	0.11
Amygdala volume a	70	−0.232	0.057	32	−0.16	0.40
Accumbens volume a	71	−0.22	0.064	32	−0.016	0.93
CSF volume a	71	0.34	0.005	32	0.16	0.40

r: Pearson’s correlation coefficient (log-NfL values used in the calculations). r: Pearson’s partial correlation coefficient adjusted for ^aage and total intracranial volume or ^bage

CSF Cerebrospinal fluid, NfL Neurofilament Light