Table 2.
Multivariate cox regression of the association between different RAR levels and in-hospital mortality
| Outcomes | Crude mode | Model 1 | Model 2 | Model 3 | ||||
|---|---|---|---|---|---|---|---|---|
| HR (95% CIs) | P value | HR (95% CIs) | P value | HR (95% CIs) | P value | HR (95% CIs) | P value | |
| RAR | 1.05 (1.03 ~ 1.07) | < 0.001 | 1.06 (1.04 ~ 1.07) | < 0.001 | 1.05 (1.03 ~ 1.07) | < 0.001 | 1.06 (1.03 ~ 1.08) | < 0.001 |
| Quintiles | ||||||||
| Q1 (< 4.06) | 1(Ref) | 1(Ref) | 1(Ref) | 1(Ref) | ||||
| Q2 (4.06–4.89) | 1.09 (0.87 ~ 1.36) | 0.474 | 1.09 (0.87 ~ 1.36) | 0.478 | 1.07 (0.85 ~ 1.34) | 0.56 | 1.05 (0.83 ~ 1.33) | 0.668 |
| Q3 (4.89-6.0) | 1.2 (0.96 ~ 1.49) | 0.104 | 1.24 (1 ~ 1.55) | 0.054 | 1.23 (0.98 ~ 1.53) | 0.072 | 1.15 (0.91 ~ 1.46) | 0.233 |
| Q4 (≥ 6.0) | 1.65 (1.35 ~ 2.03) | < 0.001 | 1.76 (1.43 ~ 2.15) | < 0.001 | 1.65 (1.34 ~ 2.04) | < 0.001 | 1.52 (1.2 ~ 1,91) | < 0.001 |
| P for trend | < 0.001 | < 0.001 | < 0.001 | < 0.001 | ||||
Cox proportional hazard regression models were used to calculate hazard ratios (HRs) with 95% confidence intervals
Crude model was adjusted for none
Model 1 was adjusted for age and gender
Model 2 was adjusted for model 1+ (MI, CHF, cerebrovascular disease, chronic pulmonary disease, rheumatic disease, diabetes, renal disease, liver disease, MV, and RRT).
Model 3 was adjusted for model 1 + model 2+ (serum hematocrit, MBP, temperature, SPO2, potassium, INR, PT, and SOFA).
MI, myocardial infarction; CHF, congestive heart failure; MV, mechanical ventilation; RRT, renal replacement therapy; MBP, mean blood pressure; SPO2, percutaneous oxygen saturation; INR, international normalized ratio; PT, prothrombin time; SOFA, Sequential Organ Failure Assessment