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. 2022 Dec 8;23:332. doi: 10.1186/s12931-022-02257-6

Table 2.

Occupational origin of interstitial lung diseases (ILD) based on the multidisciplinary discussion diagnosis

Interstitial lung disease (ILD) Count (%) Occupational origin suggested
Count (%)
ILD associated with autoimmune disease 50 (35.5) 10 (20.0)
 Scleroderma 18 (36.0) 4 (22.2)
 Rheumatoid arthritis 8 (16.0) 3 (37.5)
 Mixed connective tissue disease 5 (10.0) 1 (20.0)
 Dermatomyositis 9 (18.0) 1 (11.1)
 Sjögren syndrome 4 (8.0) 1 (25.0)
 Other autoimmune interstitial lung disease 3 (6.0) 1 (33.3)
 ANCA (anti-neutrophilic cytoplasmic autoantibody) vasculitis 7 (14.0) 0 (0.0)
  Granulomatosis with polyangiitis 4
  Eosinophilic granulomatosis with polyangiitis 2
  Unspecified ANCA vasculitis 1
Idiopathic pulmonary fibrosis (IPF)* 31 (22.0) 14 (45.2)
 Uncertain IPF or asbestosis 2
Fibrosis, unclassifiable 18 (12.8) 7 (38.9)
Pleuro-parenchymal fibroelastosis 11 (7.8)
 Idiopathic 7 0 (0.0)
 Secondary 4 1 (25.0)
Combined Pulmonary fibrosis and emphysema 11 (7.8) 4 (36.4)
Fibrotic hypersensitivity pneumonitis 9 (6.4) 1 (11.1)
Idiopathic non-specific interstitial pneumonia (NSIP) 5 (3.6) 1 (20.0)
Cryptogenic organizing pneumonia (COP) 5 (3.6) 0 (0.0)
 Secondary OP and infectious episodes 1
Asbestosis** 3 (2.1) 3 (100.0)
 Uncertain IPF or asbestosis 2
Pulmonary alveolar proteinosis 3 (2.1) 2 (66.7)
Silicosis 1 (0.7) 1 (100.0)
Drug-induced ILD 1 (0.7)
Pulmonary Langerhans cell histiocytosis 1 (0.7) 1 (100.0)
Giant cell ILD 1 (0.7)
Borderline idiopathic hypereosinophilic syndrome and eosinophilic granulomatosis with polyangiitis 1 (0.7)
Smoking-related ILD 3 (2.1)
 Smoking-related interstitial fibrosis 2
 Unspecified smoking-related interstitial fibrosis 1

For some patients, several diagnoses were retained

Statistically significant association: *p = 0.0256; **p = 0.0233