Table 2.
Demographic and summary characteristics of ALTA sub-groups based on TIMP-1 levels (all patients)
| Characteristic | Low TIMP-1 (≤ 159.7 ng/mL) (n = 60) |
High TIMP-1 (> 159.7 ng/mL) (n = 40) |
P value |
|---|---|---|---|
| Age | 50.87 ± 2.07 | 50.60 ± 2.36 | 0.934 |
| APACHE III score | 87.12 ± 3.37 | 99.75 ± 5.02 | 0.032 |
| PaO2/FIO2 | 138.53 ± 7.82 | 147.13 ± 9.38 | 0.485 |
| Patient outcomes | |||
| Ventilator-free days | 16.27 ± 1.24 | 12.45 ± 1.70 | 0.066 |
| ICU-free days | 15.17 ± 1.09 | 11.45 ± 1.55 | 0.047 |
| Organ failure-free days | 14.87 ± 1.35 | 13.60 ± 1.71 | 0.560 |
Means and SEMs were reported for continuous variables
APACHE III score Acute Physiology, Age and Chronic Health Evaluation; PaO2 partial pressure of oxygen, FIO2 fraction of inspired oxygen