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. 2022 Dec 9;22:924. doi: 10.1186/s12884-022-05260-3

Table 2.

Fetal adverse outcome by severity of HDP during pregnancy (Total)

Normal Elevated Stage1 Non-severe stage2 Severe stage2
Preterm delivery at < 37 weeks
 Frequency, n (%) 1078(10.41) 1042(10.90) 6076(10.61) 34,128(14.20) 27,838(30.86)
 OR (95% CI) ref. 1.05(0.93 ~ 1.19) 1.02(0.91 ~ 1.14) 1.42(1.25 ~ 1.62) 5.02(4.36 ~ 5.79)
 aOR (95% CI) ref. 1.08(0.95 ~ 1.23) 1.09(0.97 ~ 1.23) 1.67(1.46 ~ 1.91) 5.44(4.70 ~ 6.28)
SGA (< 10th percentile)
 Frequency, n (%) 1179(11.40) 1031(10.80) 7195(12.57) 36,925(15.37) 21,313(28.27)
 OR (95% CI) ref. 0.94(0.83 ~ 1.07) 1.12(1.00 ~ 1.25) 1.41(1.24 ~ 1.61) 3.06(2.66 ~ 3.53)
 aOR (95% CI) ref. 1.01(0.87 ~ 1.16) 1.21(1.07 ~ 1.38) 1.55(1.34 ~ 1.79) 3.20(2.74 ~ 3.73)
Stillbirth
 Frequency, n (%) 98(0.95) 78(0.82) 462(0.81) 2495(1.04) 2242(2.96)
 OR (95% CI) ref. 0.86(0.64 ~ 1.17) 0.85(0.68 ~ 1.06) 1.10(0.86 ~ 1.41) 3.20(2.51 ~ 4.08)
 aOR (95% CI) ref. 0.97(0.71 ~ 1.33) 0.97(0.77 ~ 1.23) 1.20(0.92 ~ 1.56) 2.55(1.96 ~ 3.32)
Neonatal death
 Frequency, n (%) 25(0.24) 18(0.19) 101(0.18) 501(0.21) 484(0.64)
 OR (95% CI) ref. 0.78(0.46 ~ 1.33) 0.73(0.45 ~ 1.18) 0.86(0.55 ~ 1.34) 2.66(1.71 ~ 4.15)
 aOR (95% CI) ref. 0.85(0.50 ~ 1.44) 0.81(0.51 ~ 1.29) 0.98(0.62 ~ 1.54) 2.24(1.42 ~ 3.54)
low Apgar score
 Frequency, n (%) 51(0.50) 34(0.36) 228(0.40) 1243(0.53) 1241(1.71)
 OR (95% CI) ref. 0.72(0.47 ~ 1.10) 0.81(0.60 ~ 1.10) 1.06(0.78 ~ 1.42) 3.48(2.55 ~ 4.73)
 aOR (95% CI) ref. 0.77(0.51 ~ 1.14) 0.88(0.67 ~ 1.17) 1.10(0.83 ~ 1.45) 2.92(2.20 ~ 3.89)