Table 3.

Univariable and multivariable analysis for mortality

Variable	Univariable analysis			Multivariable analysis
	Hazard ratio (95% CI)	p-value		Hazard ratio (95% CI)	p-value
Age	1.023 (0.964–1.086)	0.460
FEV1 (% predicted)	0.992 (0.953–1.032)	0.695
DLCO (% predicted)	0.972 (0.943–1.002)	0.064		0.980 (0.949–1.012)	0.212
Current smoker	0.698 (0.232–2.067)	0.692
Diabetes mellitus	1.270 (0.352–4.583)	0.715
Underlying lung disease	2.538 (0.847–7.604)	0.096		0.908 (0.150–5.493)	0.917
Cardiovascular disease	1.140 (0.393–3.303)	0.809
cTNM stage (cIA vs.)		0.841
cIB	0.705 (0.156–3.171)	0.649
cIIA	1.400 (0.178–11.013)	0.749
Thoracoscopic surgery (vs. thoraocotomy)	0.967 (0.314–2.975)	0.953
Lobectomy/bilobectomy (vs. sublobar resection)	0.202 (0.066–0.617)	0.005		0.963 (0.124–8.558)	0.972
Complete resection	0.250 (0.053–1.183)	0.080		1.262 (0.114–8.109)	0.838
Mixed histologic type	1.090 (0.301–3.943)	0.895
pTNM stage (I vs.)		<0.001			<0.001
II	0.348 (0.043–2.782)	0.319		0.348 (0.43–2.782)	0.319
III/IV	13.216 (3.382–51.646)	<0.001		13.216 (3.382–51.646)	<0.001
Adjuvant chemotherapy	0.129 (0.104–0.941)	0.039		0.554 (0.163–1.885)	0.344
Prophylactic cranial irradiation	1.881 (0.585–6.052)	0.289

CI, confidence interval; FEV1, forced expiratory volume in 1 second; DLCO, carbon monoxide lung diffusion capacity; TNM, tumor-node-metastasis; cTNM, clinical TNM; pTNM, pathological TNM.