Fig. 1.

TNF-α and IFN-β synergistically inhibit human airway epithelial cells growth. The cell viability of BEAS-2B was detected after cells were treated with different concentration of TNF-α, IFN-β, and IFN-γ as indicated for 72 h (A), different combinations of TNF-α, IFN-β and IFN-γ (20 ng/ml of each cytokine) for 72 h (B), different concentrations of IFN-β as indicated for 72 h under two concentrations of TNF-α (C), TNF-α and IFN-β (20 ng/ml of each cytokine) for 24, 48 and 72 h, respectively (D). The results are representative of at least three separate experiments. All data are shown as mean ± SEM. * p < 0.05, * * p < 0.01, * ** p < 0.001, * ** * p < 0.0001, ns, not significant. All analysis was performed using the one-way ANOVA.