Table 3.
The Mechanism Underlying the Diabetic Wound Healing of Nanoparticles
Mechanisms | Classification of Nanoparticles | Delivery Carriers | References |
---|---|---|---|
Promotion of angiogenesis | GFs | NaCMCh/PLGA NPs, | [10,24–26] |
Col-HA-GN nanofibrous membrane, AlgSulf/PCL NPs, ELPs, | [27–29] | ||
Genetic molecule | PLGA NPs, PAM-RG4 | [38,39] | |
Exosomes | FEP dressing, MC-CS HG | [33,37] | |
Small molecule compounds | EV NPs, | [67] | |
Metal NPs | SNPECHG, 11-MTA/VEGF, Biopolymer fibers, BGNs, PABC HG | [82,95,96,98,99] | |
Antibacterial action | Small molecule compounds | Chitosan, PLGA nanoparticles | [62,66] |
Metal NPs | EPL-g-butyl, FKDP, CS/Ca-AlgNP, CS-PEG, antifouling HG, VAN-AgNCs, HA, CS-HA, CNCs, LL37, BG-HG, CA-HG | [19,75,76,79–81,87,88,90,91,93,100,108] | |
Anti-inflammatory and antioxidation | Small molecule compounds | CS NPs, NP/HG, GMs/HG, PLGA nanosuspensions, NE, KCNE, CS, Liposomal nanoparticles, HG, SA wafers, HA-pep-PAMAM, ointment | [50–54,56–58,63,68–71] |
Genetic molecule | BC-HCP, β-CD-[D3]7, LPP | [22,44,45] | |
Metal NPs | AuNPs, BG/GelMA HG, GelMA HG patches, PHBV film, CNPs, Nanosilk solutions, Zwitterionic cryogel, | [92,100,102–104,106,107] |