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. 2022 Dec 8;10:tkac047. doi: 10.1093/burnst/tkac047

Table 1.

Classification of burn wound’s depth. Information from [4, 7, 9–11]

First-degree Second-degree Third-degree Fourth-degree
Depth of burn Epidermis (superficial) SPTB
Epidermis and upper 1/3 dermis
DPTB
Epidermis and dermis, affecting appendages
Full thickness (including subcutaneous fat) Extends into muscle, tendons and/or bone
Histologic findings Loss of epidermal attachment to dermis
Epidermal cells with nuclear pyknosis (shrinkage)
Loss of epidermal attachment to dermis
Vacuolar cytoplasmic disintegration of the basal cell layer
Coagulation of epidermis and dermis
Denatured collagen appears swollen and basophilic
Exudative infiltrate may be seen
Loss of regenerative niches
Carbonized surface with intense basophilic coagulated dermis.
Scant epidermal/dermal cells present
Loss of regenerative niches
Most common causes Sunburn (prolonged UV exposure) Brief contact with hot liquids, chemicals, flames or electric discharge (such as lightning) Exposure to hot liquids, chemicals, flames or electric discharge Prolonged time in direct contact with hot liquids, chemicals, flames or electric discharge
Appearance Dry burns with erythema and desquamation
Absence of blisters
Blanch with pressure
Wet/weeping burns with erythema
Blisters present
Blanch with pressure
Moist burns with erythema and a red-waxy white appearance
Blisters present easily unroof
Delayed blanch when pressure is applied
Waxy white to dark-leathery dry and inelastic burns
Do not blanch with pressure
White or black burns
Do not blanch with pressure
Sensation Painful Extremely painful Painful only with pressure Painless unless deep pressure is applied
Healing time 3–6 days 7–14 days >21 days, usually require surgical treatment Require surgical treatment to start healing
Scarring No scarring observed No scarring, but skin dyspigmentation is expected Hypertrophic and keloid scarring expected with or without skin contracture Hypertrophic and keloid scarring with severe skin contracture

SPTB superficial partial-thickness burns, DPTB deep partial-thickness burn