Table 2.

ADDomer Epitope Sequences (adapted from Vragniau et al., 2019)

Epitope name a	Primary sequence	Context
Chikungunya b	STKDNFNVYKATRPYLAH (Kam et al., 2012)	Human infectious disease
Zika	DAHAKRQTVVVLGSQEGAV (Shawan et al., 2014)
OVA	SIINFEKL (Villegas‐Mendez et al., 2010)	Human melanoma model
Newcastle	PDEQDYQIRMAKS (Cho et al., 2008)	Livestock infectious disease epitope
Gumboro	MPKTHNSGRSNVDGGGSTLHLPHLWRPLSGGGSHNAKYVSAESWGGSHPDSIHPFLASPGGGSDTLHGHGFTNWF (Wang et al., 2007)
Extended	ENLFYQSEQGGGGAGGGNNSGSGAEENSNAAAAAMQPVEDMNDHAIRGDTFATRAEEKRAEAEAAAEAAAPAAQPEVEKPQGGSGGSGGAKIEAATAAAEAKANIVASDSTRVANAGEVRGDNFAPTPVPTAESLLADVSEGTDGGSGGSGGTETTTLAVAEETSEDDDITRGDTYITEKQKREAAAAEVKK (Zubieta, Schoehn, Chroboczek, & Cusack, 2005)	For testing (the combined RGD loop sequences from human Adenovirus serotypes Ad2, Ad11 and Ad3, disassociated via flexible linker sequences)

^a The given amino acids in the table above include the epitope flanked by linker residues GGSG (N‐term) and GSGG (C‐term) for overall flexibility.

^b Chikungunya epitope consists of an N‐terminal linker residue GGSG, and a TEV protease cleavage site right before the epitope (GGSGENLYFQ'S…, and the TEV recognition site underlined, S as the first serine in epitope sequence).