TABLE 2.
Genetic polymorphisms | Genotypes | Values(n) | Frequency(%) | HWE(P-value) |
---|---|---|---|---|
ABCB1 | ||||
rs3789243 | AA/AG/GG | 14/50/39 | 13%/49%/38% | 0.748 |
rs1128503 | AA/AG/GG | 42/51/10 | 41%/50%/9% | 0.329 |
ABCC2 | ||||
rs2273697 | GG/GA/AA | 88/14/1 | 85%/14%/1% | 0.603 |
CYP1A1 | ||||
rs2606345 | CC/CA/AA | 96/7/0 | 93%/7%/0% | 0.721 |
CYP2C9 | ||||
rs1057910 | AA/AC/CC | 96/6/1 | 93%/6%/1% | 0.026 |
LEPR | ||||
rs1137101 | AA/AG/GG | 2/19/82 | 2%/18%/80% | 0.477 |
MTHFR | ||||
rs1801133 | GG/GA/AA | 51/35/17 | 50%/34%/16% | 0.016 |
rs1801131 | TT/TG/GG | 67/31/5 | 65%/30%/5% | 0.57 |
SCN1A | ||||
rs6732655 | AA/AT/TT | 4/97/2 | 4%/94%/2% | 0 |
rs6730344 | CC/CA/AA | 74/26/3 | 72%/25%/3% | 0.699 |
rs10167228 | TT/TA/AA | 1/17/85 | 1%/16%/83% | 0.884 |
rs3812718 | CC/CT/TT | 17/47/39 | 16%/46%/38% | 0.657 |
rs2298771 | CC/CT/TT | 1/18/84 | 1%/17%/82% | 0.974 |
SCN2A | ||||
rs2304016 | AA/AG/GG | 82/20/1 | 80%/19%/1% | 0.857 |
rs17183814 | GG/GA/AA | 73/28/2 | 71%/27%/2% | 0.715 |
p > 0.05 represents that the distribution of genotype follows Hardy-Weinberg equilibrium.