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. 2022 Nov 25;13:1037239. doi: 10.3389/fphar.2022.1037239

TABLE 2.

Genotype frequencies of selected variants in 103 patients.

Genetic polymorphisms Genotypes Values(n) Frequency(%) HWE(P-value)
ABCB1
 rs3789243 AA/AG/GG 14/50/39 13%/49%/38% 0.748
 rs1128503 AA/AG/GG 42/51/10 41%/50%/9% 0.329
ABCC2
 rs2273697 GG/GA/AA 88/14/1 85%/14%/1% 0.603
CYP1A1
 rs2606345 CC/CA/AA 96/7/0 93%/7%/0% 0.721
CYP2C9
 rs1057910 AA/AC/CC 96/6/1 93%/6%/1% 0.026
LEPR
 rs1137101 AA/AG/GG 2/19/82 2%/18%/80% 0.477
MTHFR
 rs1801133 GG/GA/AA 51/35/17 50%/34%/16% 0.016
 rs1801131 TT/TG/GG 67/31/5 65%/30%/5% 0.57
SCN1A
 rs6732655 AA/AT/TT 4/97/2 4%/94%/2% 0
 rs6730344 CC/CA/AA 74/26/3 72%/25%/3% 0.699
 rs10167228 TT/TA/AA 1/17/85 1%/16%/83% 0.884
 rs3812718 CC/CT/TT 17/47/39 16%/46%/38% 0.657
 rs2298771 CC/CT/TT 1/18/84 1%/17%/82% 0.974
SCN2A
 rs2304016 AA/AG/GG 82/20/1 80%/19%/1% 0.857
 rs17183814 GG/GA/AA 73/28/2 71%/27%/2% 0.715

p > 0.05 represents that the distribution of genotype follows Hardy-Weinberg equilibrium.