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. Author manuscript; available in PMC: 2022 Dec 9.
Published in final edited form as: J Investig Med. 2004 Jan;52(1):62–71. doi: 10.1136/jim-52-01-29

FIGURE 1.

FIGURE 1

Apoptosis of MRL/lpr and BALB/cJ isolated spleen cells in vivo. Spleen lymphocytes from MRL/lpr mice (that were old enough to overproduce nitric oxide) and BALB/cJ mice were isolated and analyzed for apoptosis using annexin V and propidium iodide staining and flow cytometry. A, Apoptosis of MRL/lpr spleen lymphocytes was reported as a percentage of that for BALB/cJ spleen lymphocytes. The results were an average of several experiments. Apoptosis of MRL/lpr spleen lymphocytes was greater than that seen in BALB/cJ mice (p < .05). B, The results of a single, representative experiment, reported as the percentage of all intact cells that are apoptotic.