Table 8.
Stability testing. QC samples were tested for stability after 3 freeze-thaw cycles. They were also tested overnight at the indicated temperatures. A 3- and 7- day postextraction study were also performed at 2–8°C.
| Drug/Metabolite | F/T 3 cycles | Overnight stability (%) | Postpreparation stability | |||||
|---|---|---|---|---|---|---|---|---|
| QC | % Diff | RT | 4°C | −20°C | Init % diff nom | % Diff init day 3 | % Diff init day 7 | |
| Amphetamine∗ | QC 75 | 0.69 | 2.48 | 4.91 | 3.63 | 8.95 | −1.33 | 0.61 |
| QC 800 | 6.92 | 6.21 | 8.19 | 0.45 | −0.69 | 0.16 | −1.78 | |
|
| ||||||||
| Methamphetamine | QC 75 | −2.38 | 1.39 | -0.23 | 0.72 | −1.25 | 2.61 | 6.13 |
| QC 1800 | 1.12 | 2.62 | 1.95 | 4.85 | −2.22 | −4.26 | −1.39 | |
∗ Indicates high QC of 800.