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. 2022 Nov 30;39(23-24):1665–1677. doi: 10.1089/neu.2022.0106

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© Ryosuke Hirota et al., 2022; Published by Mary Ann Liebert, Inc.

This Open Access article is distributed under the terms of the Creative Commons License (CC-BY) (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited.

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FIG. 2. — Confocal microscopic observation of spinal cords injected with adeno-associated viral vector-8-chicken beta-actin-green fluorescent protein (AAV-8-CAG-GFP—green) virus into the right cortex and AAV-8-CAG-tdTomato (red) into the left cortex. The horizontal spinal sections of the intact (A1), vehicle (B1), and mesenchymal stem cell (MSC) (C1) groups. The dashed line at the rostral area in horizontal sections (pale orange) corresponds to the coronal sections of intact (A2), vehicle (B2), and MSC (C2), respectively. The dashed line at the caudal area in horizontal sections (light green) corresponds to the coronal sections of intact (A3), vehicle (B3), and MSC (C3), respectively. Arrow in C1 and C3 shows the converged dorsal corticospinal tract (dCST) at the caudal to the lesion core only in the MSC group. Scale bars = 1 mm (A1, B1, C1) and 300 μm (A2, A3, B2, B3, C2, C3).