Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Jul 9;30(12):3601–3618. doi: 10.1016/j.ymthe.2022.07.003

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2022 The Author(s)

This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

Subcellular vector distribution and episome formation in heart and liver tissue

(A–D) Subcellular distribution of indicated AAV vector in different cell compartments (cytosol, nucleus, membrane; measured by qPCR and displayed as GFP transgene copy number concentration or as percentage distribution upon different cell fractions of heart (A and B) and liver tissue (C and D) from sham-operated mice 14 days after administration of respective vector variants. (E and F) Percentage proportion of vector genome formed as episomes in the nucleus of heart and liver tissue (n = 3). Data are means ± standard deviation. The p values were determined by one-way ANOVA with Dunnett’s multiple comparison with the parental serotype AAV2.