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. 2022 Dec 9;13:7614. doi: 10.1038/s41467-022-35337-8

Table 1.

Descriptive statistics and evidence grading of the included meta-analyses of oral conditions

Dental Caries Periodontal disease Tooth loss Edentulism Endodontic conditions Dental trauma Tooth erosion Dental implant conditions Oral lesions Bruxism Othersa
Number of meta-analyses 65 487 33 15 17 6 3 14 16 4 17
Number of studies, median (min-max) 5 (2–32) 6 (2–65) 7 (2–19) 4.5 (2–33) 3 (2–10) 4 (2–7) 9 (9–10) 7 (2–14) 2 (2–11) 17 (2–23) 6 (2–32)
Number of participants, median (min-max) 812 (124–22,338) 1001 (42–74,113,394) 20,534 (246–5,507,766) 31,855 (1,305–5,592,964) 310 (80–670,714) 1234 (380–5659) 1112 (300–1550) 676 (226–12,736) 491 (402–12,391) 3819 (180–4673) 675 (96–10,064)
Meta-analytical criterion, n (%)
 P value <10−6, n (%) 18 (27.7) 235 (48.3) 21 (63.6) 12 (80.0) 8 (47.1) 1 (16.7) 2 (66.7) 7 (50.0) 8 (50.0) 3 (75.0) 7 (41.2)
 P value <10−3, n (%) 8 (12.3) 73 (15.0) 6 (18.2) 1 (6.7) 3 (17.6) 1 (16.7) 1 (33.3) 0 (0) 0 (0) 1 (25.0) 3 (17.7)
 P value <0.05, n (%) 9 (13.9) 61 (12.5) 1 (3.0) 2 (13.3) 1 (5.9) 3 (50.0) 0 (0) 7 (50.0) 0 (0) 0 (0) 4 (23.52)
 I2 >50%, n (%) 46 (70.8) 307 (63.0) 24 (72.7) 12 (80.0) 7 (41.2) 3 (50.0) 2 (66.7) 7 (50.0) 10 (62.5) 3 (75.0) 12 (70.6)
I2 ≤25%, n (%) 13 (20.0) 133 (27.3) 3 (9.1) 3 (20.0) 8 (47.1) 3 (50.0) 0 (0) 3 (21.4) 6 (37.5) 1 (25.0) 5 (29.4)
Overall grading, n (%)
 Not significant 30 (46.2) 118 (24.2) 5 (15.2) 0 (0) 5 (29.4) 1 (16.7) 0 (0) 5 (35.7) 8 (50.0) 0 (0) 3 (17.6)
 Weak 21 (32.3) 171 (35.1) 2 (6.1) 3 (20.0) 10 (58.8) 4 (66.7) 1 (33.3) 9 (64.3) 7 (43.8) 1 (25.0) 9 (52.9)
 Suggestive 3 (4.6) 44 (9.0) 5 (15.2) 0 (0) 0 (0) 0 (0) 0 (0) 0 (0) 0 (0) 0 (0) 1 (5.9)
 Highly suggestive 7 (10.8) 107 (22.0) 13 (39.4) 10 (66.7) 1 (5.9) 0 (0) 2 (66.7) 0 (0) 1 (6.3) 3 (75.0) 2 (11.8)
 Strong 4 (6.2) 47 (9.7) 8 (24.2) 2 (13.3) 1 (5.9) 1 (16.7) 0 (0) 0 (0) 0 (0) 0 (0) 2 (11.8)

aThis group includes results from denture stomatitis, mouth breathing, salivary conditions and salivary flow rate.