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. 2022 Dec 9;13:7614. doi: 10.1038/s41467-022-35337-8

Table 2.

Descriptive statistics and evidence grading of the included meta-analyses of oral interventions

Dental Treatment Endodontic Treatment Mandibular advancement Periodontal Treatment
Number of meta-analyses 4 1 2 172
Number of studies, median (min-max) 3.5 (2–15) 3 10 (10–10) 5 (2–25)
Number of participants, median (min-max) 899 (426–2,163) 100,701 450 (400–500) 475.5 (46–7,335)
Meta-analytical criterion, n (%)
 P value <10−6, n (%) 0 (0) 1 (100.0) 1 (50.0) 32 (18.6)
 P value <10−3, n (%) 0 (0) 0 (0) 0 (0) 23 (13.4)
 P value <0.05, n (%) 0 (0) 0 (0) 0 (0) 29 (16.9)
 I2 >50%, n (%) 1 (25.0%) 0 (0) 2 (100.0) 98 (57.0)
 I2 ≤25%, n (%) 2 (50.0%) 0 (0) 0 (0.0) 57 (33.1)
Overall grading, n (%)
Not significant 4 (100.0) 0 (0) 1 (50.0) 89 (51.7)
Weak 0 (0) 0 (0) 1 (50.0) 68 (39.5)
Suggestive 0 (0) 0 (0) 0 (0) 3 (1.7)
Highly suggestive 0 (0) 0 (0) 0 (0) 11 (6.4)
Strong 0 (0) 1 (100.0) 0 (0) 1 (0.6)