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. 2022 Dec 10;12:508. doi: 10.1038/s41398-022-02274-5

Fig. 8. Torin-1 treatment reduces tau specifically in MAPT p.R406W neurons.

Fig. 8

iPSC-derived neurons from MAPT p.R406W and isogenic, controls were cultured for 6 weeks prior to treatment with torin-1 or DMSO, control for 5 h. Tau was measured in cells lysates using IP/MS. Graphs represent mean ± SEM. Significance was determined using an unpaired, t-test. *p < 0.05.