Table 1.

Lysosomal genes are differentially expressed in brains from MAPT p.R406W carriers.

Gene	Log2 Fold Change	p value
TFEB	0.91	3.63E−02
ABCB9	0.43	4.24E−02
MAN2B2	0.47	1.92E–03
SMPD1	0.51	1.51E–02
PPT2	0.53	5.15E–03
GAA	0.64	3.15E–02
ARSA	0.65	1.68E–02
CLCN7	0.82	7.49E–04
HYAL1	0.84	3.15E–03
GALNS	0.88	1.00E–04
TMEM92	0.88	1.84E–02
MAN2B1	1.03	1.16E–02
ABCA2	1.06	4.83E–02
HYAL2	1.18	2.19E–02
SGSH	1.22	2.65E–04
CTNS	1.27	8.74E–04
IDUA	1.40	6.76E–05
NEU4	1.70	7.82E–04
GGH	−1.30	9.82E–04
EPDR1	−1.27	8.67E–03
PPT1	−1.18	1.02E–05
ENTPD4	−0.79	9.87E–04
HEXB	−0.76	1.05E–02
PCYOX1	−0.75	2.06E–04
ASAH1	−0.72	2.33E–02
LMBRD1	−0.70	3.66E–03
NEU1	−0.57	4.43E–02
OSTM1	−0.56	2.23E–03
SLC17A5	−0.51	3.94E–04
GALC	−0.49	2.97E–02
CTSC	−0.44	9.03E–03
HPSE	−0.42	3.00E–02
ATG12	−0.81	2.03E–06
ATG5	−1.12	1.04E–05
ATG2A	1.17	6.16E–05
ATG2B	−0.73	1.34E–04
ATG16L1	−0.56	3.02E–03