Table 5.
Repurposed Drugs Approved for Both Common and Orphan Diseases [4]
| Compound | Common Disease | Orphan Disease | Approval Status |
|---|---|---|---|
| Azathioprine | Rheumatoid arthritis | Renal transplant | Approved |
| Bleomycin | Various cancers | Pleural effusion | Approved |
| Colchicine | Gout | Mediterranean fever | Approved |
| Cycloserine | Urinary tract infection | Tuberculosis | Approved |
| Eflornithine | Unwanted facial hair | Sleeping sickness | Approved |
| Cyclosporine | Rheumatoid arthritis Psoriasis | Transplant rejection | Approved |
| Everolimus | Renal cancer | Renal transplant | Approved |
| Histrelin | Prostate cancer | Precocious puberty | Approved |
| Interferon alpha | Hepatitis B and C | Various cancers | Approved |
| Rituximab | Rheumatoid arthritis | Various cancers | Approved |
| Infliximab | Ulcerative colitis Rheumatoid arthritis Psoriasis | Crohn’s disease | Approved |