Table 1.

Clinical and demographic features of controls, DLB, PD, and iRBD patients.

	Control (n = 147)^a	DLB (n = 28)^a		PD (n = 224)^a		iRBD (n = 26)^a
			P-value^b		P-value^b		P-value^b
Age (years)	68.3 ± 9.9	77.5 ± 5.9	5.0E-6^*	68.2 ± 8.6	0.93	74.5 ± 6.4	2.3E-3^*
# Females	69	14	0.84	130	0.043^*	6	0.031^*
Body mass index (BMI)	22.9 ± 3.0	20.9 ± 3.5	2.9E-3^*	21.7 ± 3.0	1.9E-4^*	24.4 ± 2.4	0.016^*
# Constipation (≤ twice a week)	6	12	3.6E-7^*	80	3.3E-14^*	9	2.8E-5^*
Stool frequency/week	7.9 ± 4.3	4.8 ± 4.6	7.7E-4^*	4.7 ± 4.1	6.8E-12^*	5.8 ± 5.7	0.034^*
Disease duration (years)	–	2.1 ± 2.2	–	7.5 ± 6.1	–	6.4 ± 4.8	–
# Proton pump inhibitor	12	6	0.045^*	35	0.038^*	7	0.011^*
# H₂ blocker	6	3	0.16	8	0.79	1	1.00
MDS-UPDRS	–	59.2 ± 36.2	–	50.1 ± 23.1	–	7.6 ± 5.5	–
MDS-UPDRS III	–	31.0 ± 21.0	–	26.4 ± 13.5	–	2.0 ± 2.6	–

^aMean and SD are indicated when applicable. ^bEither Student’s t-test or Fisher’s exact test is applied to be compared to controls. *P < 0.05.