Fig. 6. Assessment of bias between experiments and technologies.

a Integrated UMAP colored by sciMETv2 experiment (left) and the cluster breakdown for each experiment as well as experiment breakdown for each cluster (right). b Integration with human frontal cortex snmC-seq2 data projected into a UMAP and colored by assay (left), and by clusters (middle, non-neuron clusters are grayed out), with the cluster composition of each method (right). c Integration with a sciMETv2.LA dataset produced using three sets of 96 indexes at the tagmentation step performed on a different individual. Cells from each method were present in each cluster, though greater counts of glial cells were observed in the new preparation.