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. 2022 Dec 9;13:7627. doi: 10.1038/s41467-022-35374-3

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 7 — a UMAP projections colored by cluster for each sciMETv2 experiment when analyzed using CG methylation alone and for the integrated sciMETv2 dataset processed (right). b CG based UMAP on the integrated dataset as in a, with cells colored by CH methylation clusters that were previously determined and a confusion matrix comparing the CG (y-axis) and CH (x-axis) cluster identities.