Table 3.
Animal models | Reflection of human disease aspects |
---|---|
Cottontop tamarins | (a) EBV infection; (b) Malignant lymphomas after challenge with high doses of EBV; (c) Large-cell lymphomas with multiple copies of the EBV genome (resembles the condition of PTLD patients) |
Common marmosets | (a) EBV infection; (b) Chronic infectious mononucleosis; (c) Lymphocytosis; (d) Production of heterophile antibodies; (e) long-term production of EBV-specific antibodies |
Owl monkeys | (a) EBV infection; (b) LPD |
PTLD post-transplantation lymphoproliferative disorder, LPD lymphoproliferative disease.