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. 2022 Nov 22;14(23):5724. doi: 10.3390/cancers14235724

Table 2.

Description of cardiac mean doses and dose–volume histogram parameters.

Dosimetric Variables All Patients
N = 101		 Right-Sided BC
N = 17		 Left-Sided BC
N = 84		 Comparison Right vs. Left
Mean ± SD Mean ± SD Mean ± SD p-Value 1
Whole heart
Mean dose (Gy)
D2(Gy)
V2(%)
V5 (%)		  
2.49 ± 1.45
22.67 ± 17.85
24.0 ± 14.9
7.6 ± 6.4		  
0.61 ± 0.46
2.47 ± 1.14
6.7 ± 13.0
0.3 ± 1.0		  
2.87 ± 1.28
26.76 ± 16.83
27.4 ± 12.7
9.1 ± 6.0		  
<0.001
<0.001
<0.001
<0.001
Left ventricle
Mean dose (Gy)
D2(Gy)
V2(%)
V5 (%)		  
5.17 ± 3.72
28.62 ± 18.93
40.4 ±22.2
18.2 ± 12.5		  
0.17 ± 0.29
0.54 ± 0.60
1.0 ± 4.3
0 ± 0		  
6.18 ± 3.24
34.30 ± 15.40
48.4 ± 14.5
21.9 ± 10.3		  
<0.001
<0.001
<0.001
-
LMCA
Mean dose (Gy)
D2(Gy)
V2(%)
V5 (%)		  
1.17 ± 0.71
1.48 ± 0.91
8.9 ± 25.1
0 ± 0		  
0.63 ± 0.76
0.69 ± 0.80
8.3 ± 23.4
0 ± 0		  
1.27 ± 0.66
1.64 ± 0.84
11.7 ± 33.2
0 ± 0		  
<0.001
<0.001
0.431
-
LAD
Mean dose (Gy)
D2(Gy)
V2(%)
V5 (%)		  
13.11 ± 9.02
32.13 ± 19.25
71.9 ± 33.3
46.7 ± 28.1		  
0.28 ± 0.53
0.51 ± 0.74
6.6 ± 22.2
0 ± 0		  
15.71 ± 7.57
38.53 ± 14.14
85.1 ± 13.8
56.2 ± 20.3		  
<0.001
<0.001
<0.001
-
CX
Mean dose (Gy)
D2(Gy)
V2(%)
V5 (%)		  
1.40 ± 0.89
2.36 ± 4.79
18.3 ± 30.2
0.5 ± 4.6		  
0.28 ± 0.43
0.53 ± 0.72
2.9 ± 8.2
0 ± 0		  
1.63 ± 0.78
2.73 ± 5.16
21.4 ± 32.0
0.6 ± 5.1		  
<0.001
<0.001
<0.001
-
RCA 
Mean dose (Gy)
D2(Gy)
V2(%)
V5 (%)		  
0.82 ± 0.53
1.42 ± 0.84
5.0 ± 15.1
0.14 ± 1.48		  
1.46 ± 0.78
2.10 ± 1.23
17.5 ± 27.0
0.87 ± 3.60		  
0.69 ± 0.34
1.28 ± 0.67
2.4 ± 9.8
0 ± 0		  
<0.001
<0.001
<0.001
-

BC: breast cancer, SD: standard deviation, D2: (Gy) minimal dose received by the most irradiated 2% of structure volume, V2–V5 (in %): relative volume of the structure exposed to at least 2 or 5 Gy, respectively. LMCA: left main common coronary artery, LAD: left anterior descending artery, CX: circumflex artery, RC: right coronary artery, 1 based on Wilcoxon test.