Table 3.
Comparison of CAC (overall and by coronary artery) before RT and two years after RT.
| CAC Description | All Patients N = 101 |
Right-Sided BC N = 17 |
Left-Sided BC N = 84 |
||||||
|---|---|---|---|---|---|---|---|---|---|
| Before RT | RT+ Two Years | p-Value | Before RT | RT+ Two Years | p-Value | Before RT | RT+ Two Years | p-Value | |
| Overall CAC | |||||||||
| Non-zero CAC, N (%) | 25 (24.7%) | 30 (29.7%) | 0.062 | 3 (17.6%) | 3 (17.6%) | 1.000 1 | 22 (26.2%) | 27 (32.1%) | 0.062 1 |
| Median/Mean (± SD) | 0/35.8 (± 119.1) | 0/47.7 (± 140.0) | <0.001 | 0/3.2 (± 11.1) | 0/4.5 (± 14.9) | 0.158 2 | 0/42.4 (± 129.5) | 0/56.4 (± 151.9) | <0.001 2 |
| CAC progression, N (%) | 28 (27.7%) | 2 (11.7%) | 26 (30.1%) | ||||||
| Coronary artery-specific CAC | |||||||||
| LMCA CAC | |||||||||
| Non-zero CAC, N (%) | 2 (2.0%) | 2 (2.0%) | 1.000 | 0 | 0 | 1.000 1 | 2 (2.4%) | 2 (2.4%) | 1.000 1 |
| Median/Mean (± SD) | 0/0.3 (±2.8) | 0/ 0.5 (±4.9) | 0.157 | 0 | 0 | 1.000 2 | 0/ 0.4 (±3.1) | 0/ 0.6 (±5.4) | 0.157 2 |
| Increased CAC, N (%) | 2 (2.0%) | 0 | 2 (2.4%) | ||||||
| LAD CAC | |||||||||
| Non-zero CAC, N (%) | 20 (19.8%) | 26 (25.7%) | 0.031 | 1 (5.9%) | 2 (11.8%) | 1.000 1 | 19 (22.6%) | 24 (28.5%) | 0.062 1 |
| Median/Mean (± SD) | 0/20.6 (±58.9) | 0/ 27.6 (±74.3) | <0.001 | 0/ 0.3 (±1.5) | 0/ 1.0 (±3.4) | 0.158 2 | 0/ 24.7 (±63.9) | 0/ 33.1 (±80.5) | <0.001 2 |
| Increased CAC, N (%) | 26 (25.7%) | 2 (11.8%) | 24 (28.6%) | ||||||
| CX CAC | |||||||||
| Non-zero CAC, N (%) | 7 (6.9%) | 10 (9.9%) | 0.250 | 0 | 0 | 1.000 1 | 7 (8.3%) | 10 (11.9%) | 0.250 1 |
| Median/Mean (± SD) | 0/3.7 (±23.5) | 0/ 5.2 (±26.3) | 0.016 | 0 | 0 | 1.000 2 | 0/4.48±25.80 | 0/6.2 (±28.8) | 0.016 2 |
| Increased CAC, N (%) | 10 (9.9%) | 0 | 10 (11.9%) | ||||||
| RCA CAC | |||||||||
| Non-zero CAC, N (%) | 15 (14.8%) | 17 (16.8%) | 0.500 | 2 (11.7%) | 2 (11.7%) | 1.000 1 | 13 (15.4%) | 15 (17.8%) | 0.500 1 |
| Median/Mean ± SD | 0/11.2 (±55.2) | 0/16.3 (±68.9) | <0.001 | 0/2.8 (±11.1) | 0/3.7 (±14.7) | 0.158 2 | 0/12.8(±60.3) | 0/18.8 (±75.1) | <0.001 2 |
| Increased CAC, N (%) | 16 (16.7%) | 2 (11.7%) | 14 (16.7%) | ||||||
CAC: coronary artery calcium score, LMCA: left main common coronary artery, LAD: left anterior descending artery, CX: circumflex artery; RCA right coronary artery. CAC progression: patients with CACRT+2 years–CACBefore RT > 0; 1 based on Mac Nemar test: 2 based on Wilcoxon test for paired samples.