Figure 6.

Effects of puerarin on α₁-adrenergic contractions of human prostate tissues. Contractions were induced by the α₁-adrenergic agonists noradrenaline (A,B), phenylephrine (C,D) and methoxamine (E,F) in the presence of 100 µM puerarin (A,C,E), 10 µM puerarin (B,D,F) and corresponding amounts of solvent (methanol) for the controls added 30 min before the construction of concentration–response curves. Data from experiments with tissues from n = 5 patients are shown in each diagram. In each experiment, tissue from one patient was allocated to the control and puerarin groups. Data are means ± SDs in concentration–response curves (p-values for whole groups from two-way ANOVA), and E_max and EC₅₀ values are from all single experiments (calculated by curve fitting) in scatter plots (p-values from two-tailed t-tests).