| 5-HT3 R | 5-hydroxytryptamine type 3 receptor |
| 5-HT1A R | 5-hydroxytryptamine type 1A receptor |
| AEBSF | 4-(2-aminoethyl)benzenesulfonyl fluoride hydrochloride |
| α7-nAChR | alpha 7-nicotinic acetylcholine receptor |
| BDNF | brain-derived neurotrophic factor |
| CaMKII | calcium/calmodulin-dependent protein kinase II |
| cAMP | cyclic adenosine-monophosphate |
| CB1 | cannabinoid receptor type 1 |
| CB2 | cannabinoid receptor type 2 |
| CCI | chronic constriction injury |
| Cdk5 | cyclin dependent kinase 5 |
| CI | carrageenan injection |
| COX | cyclooxygenase |
| DOR | delta-opioid receptor |
| eIF2α | eukaryotic initiation factor-2 alpha |
| ER | endoplasmic reticulum |
| ERK | extracellular signal-regulated kinase |
| FIH | fentanyl-induced hyperalgesia |
| GABAAR | gamma-aminobutyric acid type A receptor |
| GABABR | gamma-aminobutyric acid type B receptor |
| GLT-1 | glutamate transporter-1 |
| GSK-3β | glycogen synthase kinase-3 beta |
| HSP70 | heat shock protein 70 |
| HRS | hydrogen-rich saline |
| i.g. | intragastric |
| i.p. | intraperitoneal |
| i.t. | intrathecal |
| i.v. | intravenous |
| ICR | Institute of Cancer Research |
| IRE1α | inositol-requiring transmembrane kinase endoribonuclease-1 alpha |
| IWP-2 | inhibitor of Wnt productions-2 |
| KCC2 | potassium-chloride cotransporter |
| LiCl | lithium chloride |
| mGluR5 | metabotropic glutamate receptor type 5 |
| MEK | mitogen-activated and extracellular signal-regulated kinase |
| MMP-9 | matrix metallopeptidase 9 |
| MSC | mesenchymal stem cell |
| NAC | N-acetyl-cysteine |
| NK-1 | neurokinin-1 |
| NMDAR | N-methyl-D-aspartate receptor |
| NNES | non-nociceptive environmental stress |
| NR2B | N-methyl-D-aspartate receptor subunit 2B |
| OIH | opioid-induced hyperalgesia |
| PAM | positive allosteric modulator |
| PI | plantar incision |
| PKA | protein kinase A |
| PKC | protein kinase C |
| PLGA | polylactic-co-glycolic acid |
| QST | quantitative sensory test |
| Raf-1 | rapidly accelerated fibrosarcoma 1 |
| RIH | remifentanil-induced hyperalgesia |
| s.c. | subcutaneous |
| S1PR | sphingosine-1-phosphate receptor |
| siRNA | small interfering ribonucleic acid |
| SIH | sufentanil-induced hyperalgesia |
| TDZD-8 | thiadiazolidinone-8 |
| TIH | tramadol-induced hyperalgesia |
| TLR4 | toll-like receptor 4 |
| TUDCA | tauroursodeoxycholic acid |
| TrkB/Fc | tropomyosin receptor kinase fragment crystallizable (region) |
| VGCC | voltage-gated calcium channel |
| VGSC | voltage-gated sodium channel |