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. 2022 Dec 4;11(23):3927. doi: 10.3390/cells11233927

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Hypothetical schema for the roles of Nrf2 in sepsis-induced lung injury. Nrf2 plays a protective role in sepsis-induced lung injury and inflammation through the regulation of autophagy-and NF-κB/PPARγ-mediated macrophage polarization.