FIG. 2.

DCs are superior to B cells at presenting different doses of recombinant antigen. A fixed number of DCs (solid circles) (1,000 cells/well) or fresh B cells (solid squares) (30,000 cells/well) was incubated with increasing doses of S. gordonii GP1253 and then cocultured for 3 days with specific CD4⁺ T cells (clone CP7; 30,000 cells/well). Open symbols represent T-cell proliferation in the presence of APCs treated with control strain GP1221. Results are expressed as mean cpm and SD of triplicate cultures. Similar results were observed in three independent experiments.