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. 2022 Nov 25;14(23):5801. doi: 10.3390/cancers14235801

Table 1.

Distribution of the characteristics included in the profile 1: overall population of women and focus on the families of community combinations statistically associated with BC. See Section 3.4 for the description of the communities and the families.

Women Belonging to Other Families Fuchsia Family Yellow Family Green Family Chi-Square Test All Women
Number of women 3247 1299 889 166 5601
BC prevalence [95% CI] 1.6% [1.2–2.1%] 2.5% [1.7–3.5%] (b) 0.9% [0.5–1.8%] (a) 4.2% [2.0–8.4%] (b) p = 0.004 1.8% [1.5–2.2%]
Years of age (avg ± SD)
focus on age classes
58.7 (±7.4);
> 65 * (b)
64.5 (±6.9);
60–64 ** (a);
>65 ** (b)
56.2 (±5.2);
50–54 **; 55–59 **;
60–64 * (b)
61.3 (±9.4);
45–49 **;
55–59 *; >65 **
p < 0.001 59.7 (±7.6)
Breast density: p < 0.001
BI-RADS A (less dense) 14.6% * 28.6% ** 7.3% * 21.7% 16.9%
BI-RADS B 37.1% 45.7% ** 27.7% * 45.8% ** 37.9%
BI-RADS C 36.8% ** 23.9% * 46.5% ** 25.9% * 35.0%
BI-RADS D 11.5% ** 1.7% * 18.6% ** 6.6% 10.2%
Family history of BC: p < 0.001
no first line relatives 72.5% * 78.6% ** 69.4% * 76.5% 73.5%
first line female relatives 25.5% 21.4% * 29.7% ** 23.5% 25.2%
first line male relatives 0.5% 0.0% * 0.9% ** (b) 0.0% 0.4%
first line male and female rel. 1.5% 0.0% 0.0% 0.0% 0.9%
Menarche age (avg. years ± SD) 12.6 (±1.4) 12.4 (±1.4) 12.7 (±1.4) 12.8 (±1.5) 12.6 (±1.4)
Reproductive period length 37.4 (±4.2) 38.8 (±3.9) 37.7 (±3.3) 32.1 (±3.4) 37.6 (±4.1)
Menopause (avg. years ± SD).
Focus on length classes
8.6 (±7.3)
≤5 **; >5 *
13.3 (±7.7)
≤5 *; >5 **
5.9 (±5.7);
≤5 ** (a); >5 * (b)
16.5 (±10.2)
≤5 *; >5 **

p < 0.001
9.5 (±7.7)

Association between each risk factor and family (chi-square test p < 0.05): * negative (adj. residual < −2); ** positive (adj. residual > 2); Association between BC cases and each risk factor by family (chi-square test p < 0.05): (a) negative (adj. residual < −2); (b) positive (adj. residual > 2).