Table 2.
Distribution of the characteristics included in the profile 2: overall population of women and focus on the families statistically associated with BC. See Section 3.4 for the description of the communities and the families.
| Women Belonging to Other Families | Fuchsia Family | Yellow Family | Green Family | Chi-Square Test | All Women | |
|---|---|---|---|---|---|---|
| Number of women | 3247 | 1299 | 889 | 166 | 5601 | |
| BC prevalence [95% CI] | 1.6% [1.2–2.1%] |
2.5% [1.7–3.5%] (b) | 0.9% [0.5–1.8%] (a) |
4.2% [2.0–8.4%] (b) |
p = 0.004 | 1.8% [1.5–2.2%] |
| Qualification: | p < 0.0010 | |||||
| primary secondary education | 24.1% * | 34.4% ** | 19.1% * | 36.1% ** | 26.1% | |
| high school graduation | 40.9% ** | 35.0% * | 39.6% | 34.9% | 39.2% | |
| university/post graduate | 35.0% | 30.6% * | 41.3% ** | 28.9% | 34.8% | |
| Occupation: | p < 0.001 | |||||
| unemployed/housewife | 33.3% * | 59.3% ** | 19.7% * | 53.6% ** | 37.8% | |
| employed | 63.8% ** | 36.1% * | 73.1% ** | 42.8% * (a) | 58.2% | |
| retired | 0.6% * | 4.5% ** | 0.0% * | 3.6% ** | 1.5% | |
| work/worked night shifts | 2.3% | 0.0% * | 7.2% ** | 0.0% * | 2.5% | |
| Current or past Co-morbidities: | p < 0.001 | |||||
| 1 co-morbidity | 27.8% | 24.9% * | 35.5% ** | 26.5% | 28.3% | |
| at least 2 co-morbidities groups | 56.3% * | 68.0% ** | 51.9% * | 66.9% ** | 58.6% | |
| Types of comorbidities: | ||||||
| cardiometabolic diseases | 55.6% * | 70.4% ** | 51.5% * | 63.3% | p < 0.001 | 58.6% |
| endocrine diseases | 49.5% | 52.1% | 53.1% | 56.0% | p > 0.05 | 50.9% |
| intestinal diseases | 11.3% | 13.0% ** | 8.8% * | 11.4% | p = 0.024 | 11.3% |
| neuropsychiatric diseases | 39.3% * | 44.5% ** | 40.7% | 53.6% ** (a) | p < 0.001 | 41.2% |
| autoimmune diseases | 23.3% * | 30.1% ** | 21.8% * | 21.7% | p < 0.001 | 24.6% |
| Chest radiation therapy | 6.5%* (b) | 13.7% ** | 4.5% * | 18.1% ** | p < 0.001 | 8.2% |
| Pregnancy (at least one) | 80.0% | 88.8% ** (b) | 68.4% * | 86.1% (a) | p < 0.001 | 80.4% |
| Breast feeding | 63.1% | 73.2% ** | 53.5% * (a) | 69.3% | 64.1% | |
| BMI: | p < 0.001 | |||||
| underweight (<18.5) | 6.1% ** | 0.4% * | 0.3% * | 0.0% * | 3.7% | |
| normal weight (18.5–24.9) | 68.2% | 56.5% * | 80.9% ** | 59.0% * | 67.2% | |
| overweight (25–29.9) | 20.5% * | 29.6% ** | 15.0% * | 28.9% ** | 22.0% | |
| obese (≥30) | 5.2% * | 13.5% ** | 3.8% * | 12.0% ** | 7.1% | |
| Weight gain in menopause | 55.0% * | 67.9% ** | 54.2% * | 70.5% ** | p < 0.001 | 58.3% |
| Oral contraceptive use: | p < 0.001 | |||||
| never or less than 1 year | 46.9% * (b) | 59.3% ** | 42.4% * | 59.0% ** | 49.4% | |
| 1–5 years | 25.1% ** | 22.3% | 21.4% | 18.7% | 23.7% | |
| more than 5 years | 28.0% ** | 18.4% * | 36.2% ** | 22.3% | 26.9% | |
| Ovarian stimulation: | p < 0.001 | |||||
| at least 1 cycle of stimulation | 6.8% | 2.9% * | 14.1% ** | 3.0% | 6.9% | |
| HRT: | p < 0.001 | |||||
| more than 6 months | 17.9% * | 23.9% ** | 14.6% * | 38.6% ** | 19.4% |
Association between each risk factor and family (chi-square test p < 0.05): * negative (adj. residual < −2); ** positive (adj. residual > 2); Association between BC cases and each risk factor by family (chi-square test p < 0.05): (a) negative (adj. residual < −2); (b) positive (adj. residual > 2).