Table 2.
Echocardiographic and laboratory findings in 84 patients with infective endocarditis.
| Total (n = 84) |
C. burnetii and Bartonella (n = 23, 27.4%) |
Staphylococcus aureus (n = 31, 36.9%) |
Streptococcus (n = 30, 35.7%) |
p Value | |
|---|---|---|---|---|---|
| Affected valve | |||||
| Left-side endocarditis | 82 (98) | 23 (100) | 29 (93) | 30 (100) | <0.001 |
| Only aortic valve, n (%) | 37 (44) | 19 (83) | 13 (42) * | 5 (17) * | |
| Only mitral valve, n (%) | 27 (32) | 1 (4) | 10 (32) * | 16 (53) * | |
| Aortic valve and mitral valve, n (%) | 18 (21) | 3 (13) | 6 (19) | 9 (30) | |
| Right-side endocarditis | 8 (10) | 1 (4) | 4 (13) | 3 (10) | 0.595 |
| Only tricuspid valve, n (%) | 8 (10) | 1 (4) | 2 (7) | 3 (10) | |
| tricuspid valve and pulmonary valve, n (%) | 2 (2) | 0 | 2 (7) | 0 | |
| CABV, n (%) | 30 (36) | 15 (65) | 11 (36) | 4 (13) # | <0.001 |
| Cardiac complication | |||||
| Abscess, n (%) | 37 (44) | 15 (65) | 19 (61) | 3 (10) # | <0.001 |
| Fistula, n (%) | 16 (19) | 10 (44) | 5 (16) | 1 (3.3) # | <0.001 |
| Valve perforation, n (%) | 42 (50) | 14 (61) | 17 (55) | 11 (37) | 0.173 |
| Pseudoaneurysm, n (%) | 7 (8.3) | 3 (13) | 4 (13) | 0 | 0.089 |
| Vegetation Diameter, mm, median (IQR) | 13.0 (8) | 12.5 (5.9) | 11.5 (10.7) | 14.5 (6.5) | 0.273 |
| LVEF, %, median (IQR) | 61 (17) | 61 (16) | 64 (6) | 66 (6) * | 0.042 |
| Preoperative laboratory test | |||||
| PCT, ng/mL, median (IQR) | 0.20 (1.1) | 1.10 (2.55) | 0.24 (1.34) | 0.17 (0.29) | 0.128 |
| WBC, 109/L, median (IQR) | 8.4 (5.6) | 7.1 (2.3) | 10.7 (9.7) * | 8.7 (4.7) | 0.002 & |
| NEUT, %, median (IQR) | 76 (21) | 60 (21) | 79 (16) * | 78 (14) * | <0.001 |
| Monocyte/Lymphocyte, median (IQR) | 0.54 (0.69) | 0.34 (0.29) | 0.98 (1.03) * | 0.62 (0.45) | <0.001 |
| PLT, 109/L, median (IQR) | 204 (135) | 180 (52) | 206 (119) | 231 (122) * | 0.007 |
| Albumin, g/L, median (IQR) | 33 (8) | 37 (7) | 31 (9) * | 33 (9) | 0.005 & |
| TBIL, μmol/L, median (IQR) | 14 (12) | 21 (15) | 15 (10) | 12 (7) | 0.147 |
| DBIL, μmol/L, median (IQR) | 4 (5) | 5 (6) | 4 (3) | 3 (5) | 0.222 |
| Pro-BNP, median (IQR) | 2704 (5230) | 3543 (4681) | 2019 (8666) | 1085 (4423) | 0.228 |
| Positive blood culture, n (%) | 13 (15) | 0 | 7 (23) | 6 (20) | 0.034 |
| Positive tissue culture, n(%) | 6 (7) | 0 | 4 (13) | 2 (6.7) | 0.228 |
Continuous data are presented as the median (IQR), and categorical data are presented as n (%). CBAV Congenital bicuspid aortic valve, LVEF left ventricular ejection fraction, PCT procalcitonin, WBC white blood cell, NUET neutrophil ratio, PLT platelet, TBIL total bilirubin, DBIL direct bilirubin, pro-BNP pro-atrial natriuretic peptide. * Compared with the C. burnetii and Bartonella endocarditis groups by Dunnett’s test, p < 0.05. # Compared with the C. burnetii and Bartonella endocarditis groups by the chi-square test, p < 0.017. & Welch test.