Table 2.
Univariable and multivariable logistic regression analysis of lipid peroxidation at the time of hospital admission.
| Variable | Univariable | Multivariable | ||
|---|---|---|---|---|
| OR (95% CI) | p-Value | OR (95% CI) | p-Value | |
| Age | 1.007 (0.971–1.045) | 0.700 | ||
| Male gender | 0.883 (0.320–2.435) | 0.810 | ||
| Total cholesterol | 0.986 (0.969–1.002) | 0.092 | 0.982 (0.969–0.996) | 0.012 |
| IL1RA | 0.999 (0.998–0.999) | 0.017 | 0.999 (0.998–0.999) | 0.021 |
| IL-2 | 0.961 (0.862–1.070) | 0.467 | ||
| IL-4 | 0.991 (0.825–1.191) | 0.927 | ||
| IL-5 | 0.996 (0.976–1.017) | 0.703 | ||
| IL-6 | 1.094 (1.026–1.166) | 0.006 | 1.062 (1.017–1.110) | 0.007 |
| IL-7 | 0.582 (0.311–1.087) | 0.089 | 0.653 (0.433–0.986) | 0.042 |
| IL-8 | 0.983 (0.952–1.015) | 0.302 | ||
| IL-9 | 0.797 (0.512–1.240) | 0.314 | ||
| IL-12p70 | 0.856 (0.480–1.528) | 0.600 | ||
| IL-15 | 1.018 (0.931–1.112) | 0.702 | ||
| IL-17α | 1.200 (0.998–1.442) | 0.052 | 1.098 (1.010–1.193) | 0.028 |
| IL-18 | 1.010 (0.996–1.023) | 0.164 | ||
| IL-23 | 1.449 (0.951–2.208) | 0.084 | ||
| IL-31 | 0.735 (0.535–1.009) | 0.057 | ||
| IP-10 | 0.995 (0.987–1.003) | 0.225 | ||
The outcome of interest is LPO > 1948.17 μM, which is independently associated with COVID-19 mortality [10]. Significant values (p < 0.05) are bold. Abbreviations: IL—interleukin; IP-10—interferon-γ-inducible protein 10; LPO—lipid peroxidation; OR—Odds ratio.